AibGenesis™ Mouse Anti-PDHX Antibody (CBMOAB-54166FYA)

Name: AibGenesis™ Mouse Anti-PDHX Antibody (CBMOAB-54166FYA)
SKU: CBMOAB-54166FYA
Rating: 5 (1 reviews)

Cat: CBMOAB-54166FYA

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-54166FYA	Monoclonal	Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Mallard (Anas platyrhynchos), Marmoset, Zebrafish (Danio rerio)	WB, ELISA	MO54166FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 501 amino acids long. The sequence is show below: MAASWRLGCDPRLLRYLVGFPGCRSIGLVKGALGWSVSRGANWRWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPRTLRFRLSPAARNILEKHSLDASQGTATGSFSIGSKSKCFKILDMVRTSSIPCLLKVRVEKSVPDASSPLYLTKIPLFYRVIQSPKQTHLWRNYLGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENPIRLA.
CBMOAB-92061FYA	Monoclonal	Zebrafish (Danio rerio)	WB, ELISA	MO92061FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 496 amino acids long. The sequence is show below: MAASMRLGRRTLFTALRALTQTPAGLQSSFRPPRESPRPAGWSRSAARPLYQSCRARAGVCPLKVQMPALSPTMEEGNIVKWLKKEGEDVAAGDALCEIETDKAVVVMESNEDGVLARILVQEGSRGVRLGTLIALMVSEGEDWKQVEIPALESVTPPTAAPPTAAPPTAGSAPPAAPALRQSVPTPLLRLSPAARHILDTHGLDPHQATASGPRGIITKEDALKLLSKASAAPPAAAAPAPSAPPAAPPAARPPHPPASAPARSAAPGTFTEIPASSVRRIIAQRLTQSKTTIPHTYACIHCDISGVMRVRKRLAEENIKVSVNDFIIKAAAVSLRELPAVNVSWSADGPQPLGFIHISMAVATDRGLITPIIRDAADKGLQEISSTAKALAQKARDGKLLPEEYQGGSFSVSNLGMFGISEFSAVINPPQACILAVGGSRTELSLSAEDTLQTQHTLTVTLSSDARLVDDELASRFLETFRSNLERPERMSLQA.
MO-AB-06138H	Monoclonal	Frog (Xenopus laevis)	WB, ELISA	MO06138C		100 µg	Inquiry
Protein Refseq: The length of the protein is 478 amino acids long. The sequence is show below: MAASLRLGCQGLIRSFLGGLRTHSGECSLRALHTAGTLRGVPGVQVSMPALSPTMEEGNIVKWLKKEGESVSAGDALCEIETDKAVVTMESNDDGVLAKILVEEGSKNVRLGSLIALLVEEGQDWKQVHVPSVKVSPTTVAAATKIANVAPVAKRGLRMSPAARHIIDTHGLDTGSITPSGPRGIITKEDALKCLAQKEVPGEKPKPAAPTPTLQKISTSPPAASPAPVSGRLTFPPMSIPGKPHTEGMFSEIPASNIRKVIAKRLTESKSSIPHAYATTDCNLGAVLQLRKELAKDNIKVSVNDFIIKATAAALKQMPNVNVTWNGEGATTLESIDISIAVATDRGLITPIIKQAASKGIQEIAATAKVLAQKARDGKLLPEEYQGGSFSISNLGMFGITGFSAVINPPQSCILAVGRSRVELGFSEGEEGNPQLCQKQVMNVTLSSDGRLVDDELATKFLECFRKNLENPLHCALV.
MO-AB-11129W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO11129W		100 µg	Inquiry
Protein Refseq: The length of the protein is 501 amino acids long. The sequence is show below: MAASWRLGCDPRLLRYLVGFPGRRSVGLVKGALGWSVSRGANWRWFNSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPAATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENPIRLA.
MO-AB-17707R	Monoclonal	Cattle (Bos taurus)	WB, ELISA	MO17707R		100 µg	Inquiry
Protein Refseq: The length of the protein is 501 amino acids long. The sequence is show below: MAASWRLGCDPRLLRCLLGFGSRRSPELVKGAARWSVGRGASWRWFHSTQWLRADPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVAEGSKNIRLGSLIGLLVEEGEDWKHVEIPKDTGPPPPAAKPSVPPPSAEPQIATPVKKEHPPGKVQFRLSPAARNILEKHALDANQGTATGPRGIFTKEDALKLVQLKQTGKITEPRPTAALPTTPAAPLPPQAAATASY.
MO-AB-23583H	Monoclonal	Mallard (Anas platyrhynchos)	WB, ELISA	MO23583C		100 µg	Inquiry
Protein Refseq: The length of the protein is 458 amino acids long. The sequence is show below: GTPAIKVLMPALSPTMEEGNIVKWLKKEGETVNAGDALCEIETDKAVVTMESSDDGVLAKILVEEGSKNVRLGSLIGLLVEEGQDWKQVEIPADASDPSSLAPPAAAPTSTPASPSVSAPPPKLEHPPGKLQVRLSPAARNILETHGLDPSNVTPSGPRGIFTKEDALKLLQEKQKDKPSELKPMVSPAPPQPSAVPSASPATAVTSAYPRPAVPPLSTPGQPAAPGTFTEIPASNIRRVIAKRLTESKTTIPHAYAAADCDIDAILKLRTELAKADDIKVSVNDFIIKATAVTLKQMPDVNATWDGEGCRQLQSIDISIAVATDRGLITPIIKDVAAKGIQEIAASAKALAKKARDGKLLPEEYQGGSFSISNLGMFGINDFTAVINPPQACILAVGRARPELKVVEDEEGNEKLKQHQLMTVTLSSDGRVVDDELASKFLETLKANLENPIRLALC.
MO-AB-61228W	Monoclonal	Marmoset	WB, ELISA	MO61228W		100 µg	Inquiry
Protein Refseq: The length of the protein is 502 amino acids long. The sequence is show below: MAASWKLGCDPRLLRYLVGFPGRRSIPGLVKGAVGWSVTRGSSWRWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVNAGDALCEIETDKAVVTLDASDDGILAKIVVEEGTKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPPSKPSEPRPSPEPQVAIPVKKEHTPGTLQFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALRLAQLKQMGKITESRPTPAPAATPTAPSPLQATAGPSYPRPMIPPVSTPGQPFAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPCIDISVAVATDKGLITPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENPIRLA.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Mallard (Anas platyrhynchos), Marmoset, Zebrafish (Danio rerio)
Clone	MO54166FYA
Specificity	This antibody binds to Rhesus PDHX.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood. This protein is also a minor antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC eventually leads to cirrhosis and liver failure. Alternative splicing results in multiple transcript variants encoding distinct isoforms. (From NCBI)
Product Overview	Mouse Anti-Rhesus PDHX Antibody is a mouse antibody against PDHX. It can be used for PDHX detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	PDHX
UniProt ID	F7HS46
Protein Refseq	The length of the protein is 501 amino acids long. The sequence is show below: MAASWRLGCDPRLLRYLVGFPGCRSIGLVKGALGWSVSRGANWRWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPRTLRFRLSPAARNILEKHSLDASQGTATGSFSIGSKSKCFKILDMVRTSSIPCLLKVRVEKSVPDASSPLYLTKIPLFYRVIQSPKQTHLWRNYLGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENPIRLA.

For Research Use Only | Not For Clinical Use.

Online Inquiry