Mouse Anti-Robo3 Antibody (CBMOAB-29862FYA)

Cat: CBMOAB-29862FYA

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Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-29862FYA	Monoclonal	Fruit fly (Drosophila melanogaster), D. melanogaster (Drosophila melanogaster), Frog (Xenopus laevis), Rhesus (Macaca mulatta), Zebrafish (Danio rerio)	WB, ELISA	MO29862FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 1342 amino acids long. The sequence is show below: MDLRFVFIVFLLKWTHAQGSHPPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAGGLFFLKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRIAQGDTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGNLAIQDARQTDEGQYQCIAKNPVGVRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVGGDPMPDVLWLRTASGGNMPLDRVSVLEDRSLRLERVTIADEGEYSCEADNVVGAITAMGTLTVYAPPKFIQRPASKSVELGADTSFECRAIGNPKPTIFWTIKNNSTLIFPGAPPLDRFHSLNTEEGHSILTLTRFQRTDKDLVILCNAMNEVASITSRVQLSLDSQEDRPPPIIISGPVNQTLPIKSLATLQCKAIGLPSPTISWYRDGIPVQPSSKLNITTSGDLIISDLDRQQDQGLYTCVASSRAGKSTWSGFLRIELPTNPNIKFYRAPEQTKCPSAPGQPKILNATASALTIVWPTSDKAGASSFLGYSVEMYCTNQSRTWIPIASRLSEPIFTVESLTQGAAYMFIVRAENSLGFSPPSPISEPITAGKLVGVRDGSESTGTSQLLLSDVETLLQANDVVELLEANASDSTTARLSWDIDSGQYIEGFYLYARELHSSEYKMVTLLNKGQGLSSCTVPGLAKASTYEFFLVPFYKSIVGKPSNSRRMRTLEDVPEAPPYGMEAIQFNRTSVFLKWLPPQPNRTRNGILTSYNVVVKGLDVHNTTRIFKNMTIDAAAPTLLLANLTTGVTYYIAVAAATRVGVGPFSKPAVLRIDARTQSLDTGYTRYPISRDIADDFLTQTWFIVLLGSIIAIIVFLLGALVLFKRYQFIKQTSLGSLHGNHAIGTVRKFPTLPLNGGGAVGAGGSNSTAAAGQSGHGLWIDPTSGVWRQAAGGGNPGGVGSCTTKEQLPGYAQATAQQGQQPTLLPDYERLSPLNMPDYAEVACSTFKSPTHGAPPMGGGGGGQSASLYDSCGAYATTNVVANVKLYQNRYATKPNQSSGSNNNNHQGNDYQSTGMYSAPPSAHYGCLEPKQQQQQQQPNLMTTSTASTAILTNSPAKVKKINITENKMDQLEGKSERTNPFNQQQQLLLASNALKQGLGAYANTTLAAQMASGGGAGTLRRQRQPKTLYKSENNILGKSGLRQNTMNASVGAPSNGQMDFLTGGPPSEGGDFSGLGLCNSTNQLLNDWASSASIAAPGDYHFGSKQPSKQHLYVKAKDGTWSAVSSDAYQSFKHQQQHHPFLAGSGDNTKSLASVNSLAGDSKFLSSFGSSANV.
CBMOAB-56695FYA	Monoclonal	Rhesus (Macaca mulatta)	WB, ELISA	MO56695FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 268 amino acids long. The sequence is show below: VSFPHSEGLSGASSRPPMGLGPAPYPWLADSWPHPSRSPSAQEPRGSCCPSNPDPDDRYYNEAGISLYLAQTARGTAAPGEGPVYSTIDPAGEELQTFHGGFPQHPSGDAGPWSQYAPPEWSQGDSGAKGGRVKLLGKPVQMPSLNWPEALPPPPPSCELSCLEGPEEELEGSSEPEEWCPPMPERSHLTEPSSSGGCLVTPSRRETPSPTPSYGQQSTATLTPSPPDPPQPPTDMPHLHQMPRRVPLGPSSPLSVSQPMLGIREGRP.
CBMOAB-96290FYA	Monoclonal	Zebrafish (Danio rerio)	WB, ELISA	MO96290FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 1419 amino acids long. The sequence is show below: MLRYLIKTLLQMNLFTDTIRDATNGTDLFFNISSIPSFNSSLLDWANFTGLNGSRPRLEDAAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQTPSDVVVAAGEPAVMECIPPRGHPEPTISWKRNNVKVNDKDERITIRGGKLMISNTRKSDAGMYVCVGTNMVGEKDSDPAELVVFERPMFVRRPVNQVVLADDTVDFQCEVQGDPAPTIRWKKEEGELPRGRFEIRADNSLRLTQVKAEDEGSYTCLSENSVGKAEASGSLQVHVPPQIVVRPRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSLSGELTITDVHSEDSGYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLAPGTTAQLQCHVMGNPLPSIQWERDGQRILGIDERISLMENGTLQITALQETDSGAYTCVASSLSGETSWSGVLTVKESGGLSASPVSEPYQLPGPPQKPVVTDVTRNSVTLTWQPNAHEGGAAVTSYIIEAFSQSAGSTWQTVADFVKLEKHTVTGLSPNTIYLFIVRAVNAYGLSDPSPISEPVRTQDVSPTGQGVDHRQVQRELGEMSVQLHEPVLLTASSVKISWNVDRQSQYIQGYRLLYRPVGGSWSQQEVKGATERSAVIANLLKGTEYEIKIRPYFNEFQGLDSRSQTLRTPEEVPSAPPRAVNVATVKLSNSSSISVSWQPPPTDMQNGVIQEYKVWCLGNDSQTRYNINQTVDGSVLSTVLKGLLPGVLYQVEVAAVTSAGVGKHSQPVSVLIKLPAEQPTVTGGGSESEENVSLAEQITDVVKQPAFIAGIGGACWVILMGFSVWIYCRRKKRKELSHYTASFAYTPAVGFPHGESSGLNGRPGMLGANMGNYPWLADSWPTTNLVHNGKDSVNCCTSKHETPERYYNEAGISNYLNQNEKYSADSNEGPIYSTIDPTSEDLRSFTAQYSQHTTPYASTPIMPFTNQAPCSPEQDGSHWMTQPGTSNAQYAQPDRSKTENVKQPKQKLMGKPVKTPSLNWMDALPPPPISGDLEQCDEEDDNELIQDMGSDEEEWCPPLPERSYLMDGMVEDGPVPPPRGEASSPTTSYSHQSTATLTPSPRDDGHFHDIPRLHQLEQPHMTRRLPCGPVHVPRAPSPPLTQSNPNLSANQECPDNTVPHRSAHKRDLSQGAAQSVENISNTTPGRARPSADHTPSGQKSKVKKKASKSAQYRRDILQGDLPPPPEPPPEDQDNCAHVGGFECGQTSLERAGSSNSSMERREQSTPNRKNSAHRRIDDDDLIPYNKPNFLSRGQMSSNCSTTGSSSSRGSTGSRGQGTGRKRNDEMR.
MO-AB-07198H	Monoclonal	Frog (Xenopus laevis)	WB, ELISA	MO07198C		100 µg	Inquiry
Protein Refseq: The length of the protein is 1396 amino acids long. The sequence is show below: MAKQKIMCFMGKTFTWILVVSVCPVLGSRPRLEDFPPRIVEHPSDHIVSKGEPATLNCKAEGRPTPIIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGVYICVARNYLGESVSRNASLEVAILRDDFRQTPNDVVVAAGEPAVMECIPPRGHPEPTISWKKDNMRISDKDERITIRGGKLMISNTRKSDAGRYICVATNMVGERDSEPAQLVVFERPTFIRRPINQVVLADDMVDFNCEVQGDPVPTARWRKEEGELPRGRYEILNDNTLRISRVSADDEGTYTCITENSVGKSEASGSLGVHVGPFLPPQLVTRPRDQIVVQGRTVTFQCETKGNPPPAVFWQKEGSQILLFPSQPPQTVGRFSVSPSGELTIIDVQTGDSGYYMCQAISVAGSILAKALLEVEDATSDKIPPIIRRGPANQTLAVDSTVQMHCQVSGNPLPSIHWLKDGQRIVGSDPRIGVLDSGNLQITHLQVTDSGVYTCVATSSTGETTWSGFIEVQEKGSLIHVQLSEPSLFRGSPSKPLVTDVTKNSVTLTWQPNPQAGNTQVHSYIIEAFSQSAGSTWQTVADSVKVEKHTVVGLNPNTVYLFIIRAVNSYGISDPSPISEPVRTQDVSPTRQGVDHRQVQRQLGEVVVQLQQPIILTSSTVQITWTVDRQAQFIQGYRVMYRPKSSVWLVQDVKSPSERNTILVDLKKGTEYEIKIRPYFDEFQGMDSDVLLIRTPEEVPSAPPQAVSVVTLGTNNSTNISISWEPPLVEHQNGIIQDYRIWVLGNETRYHINRTVDGTVHSTEVRGLTPGVLYRVEVAAATSAGFGVKSQPITIQIKPSSDHIPEASGENVSLTEQITDVVKQPAFIAGIGGACWVILMCFSVWIYCRRKKRKELSHYTASFAYTPTVSFPESSGHITARPGMLATSASNYPWLADSWPATNLLRNGKPKEPAVNCCPGNHNPSERYYNDAGISNYIAQTEKFGTAVSDGPIYSTIDPTNDDMRTFNGAFSQHTTPYATTPVVPYGGQNLHSPELEENQWNVQAGTSGVLYAQPDRTNAENVCKSGKQKAMGKPVKTPSLNWTEILPPPPPANELNHYQQGDTDVEMSSDTEEWCPPLPERTYLMENIQEGCPPPPPRGEASSPAHSYGQQSTATLTPSPRDEIHATEDIPRLHQFEIPPHPRRMPAGSVPIPRAPSPPLTQSNPSLHTVVEGTEAQRQGHRRNLSQNPNLSAENVNMPNSGKSQLSENISTPPGQKSRAKKKSKSGLYRREAKQGDLPPPPEPPPADEEPCSPHTNGPRMECLASSLERDTSTSSVERRNGAIQHRGAAGPQFHQRDDEEIIPYSKPNFLSRSQMSSNCSTTGSSSSRGSAGSRGQASGRSKTGDRKEEKR.
MO-NAB-00610W	Monoclonal	D. melanogaster (Drosophila melanogaster)	WB	NW0532		100 µg	Inquiry
MO-NAB-00613W	Monoclonal	D. melanogaster (Drosophila melanogaster)	IA	NW0535		100 µg	Inquiry

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Fruit fly (Drosophila melanogaster), D. melanogaster (Drosophila melanogaster), Frog (Xenopus laevis), Rhesus (Macaca mulatta), Zebrafish (Danio rerio)
Clone	MO29862FYA
Specificity	This antibody binds to fruit fly Robo3.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Plasma Membrane; Other locations

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	This gene is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth, growth cone guidance, and axon fasciculation. ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily. SLIT proteins 1-3, a family of secreted chemorepellants, are ligands for ROBO proteins and SLIT/ROBO interactions regulate myogenesis, leukocyte migration, kidney morphogenesis, angiogenesis, and vasculogenesis in addition to neurogenesis. This gene, ROBO3, has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs, a transmembrane segment, and a cytoplasmic tail with three conserved signaling motifs: CC0, CC2, and CC3 (CC for conserved cytoplasmic). Unlike other ROBO family members, ROBO3 lacks motif CC1. The ROBO3 gene regulates axonal navigation at the ventral midline of the neural tube. In mouse, loss of Robo3 results in a complete failure of commissural axons to cross the midline throughout the spinal cord and the hindbrain. Mutations ROBO3 result in horizontal gaze palsy with progressive scoliosis (HGPPS); an autosomal recessive disorder characterized by congenital absence of horizontal gaze, progressive scoliosis, and failure of the corticospinal and somatosensory axon tracts to cross the midline in the medulla. Alternative transcript variants have been described but have not been experimentally validated.
Product Overview	Mouse Anti-D. melanogaster Robo3 Antibody is a mouse antibody against Robo3. It can be used for Robo3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	LP22668p; Robo3, isoform A; Robo3, isoform B; robo3
UniProt ID	Q9VPZ7
Protein Refseq	The length of the protein is 1342 amino acids long. The sequence is show below: MDLRFVFIVFLLKWTHAQGSHPPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAGGLFFLKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRIAQGDTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGNLAIQDARQTDEGQYQCIAKNPVGVRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVGGDPMPDVLWLRTASGGNMPLDRVSVLEDRSLRLERVTIADEGEYSCEADNVVGAITAMGTLTVYAPPKFIQRPASKSVELGADTSFECRAIGNPKPTIFWTIKNNSTLIFPGAPPLDRFHSLNTEEGHSILTLTRFQRTDKDLVILCNAMNEVASITSRVQLSLDSQEDRPPPIIISGPVNQTLPIKSLATLQCKAIGLPSPTISWYRDGIPVQPSSKLNITTSGDLIISDLDRQQDQGLYTCVASSRAGKSTWSGFLRIELPTNPNIKFYRAPEQTKCPSAPGQPKILNATASALTIVWPTSDKAGASSFLGYSVEMYCTNQSRTWIPIASRLSEPIFTVESLTQGAAYMFIVRAENSLGFSPPSPISEPITAGKLVGVRDGSESTGTSQLLLSDVETLLQANDVVELLEANASDSTTARLSWDIDSGQYIEGFYLYARELHSSEYKMVTLLNKGQGLSSCTVPGLAKASTYEFFLVPFYKSIVGKPSNSRRMRTLEDVPEAPPYGMEAIQFNRTSVFLKWLPPQPNRTRNGILTSYNVVVKGLDVHNTTRIFKNMTIDAAAPTLLLANLTTGVTYYIAVAAATRVGVGPFSKPAVLRIDARTQSLDTGYTRYPISRDIADDFLTQTWFIVLLGSIIAIIVFLLGALVLFKRYQFIKQTSLGSLHGNHAIGTVRKFPTLPLNGGGAVGAGGSNSTAAAGQSGHGLWIDPTSGVWRQAAGGGNPGGVGSCTTKEQLPGYAQATAQQGQQPTLLPDYERLSPLNMPDYAEVACSTFKSPTHGAPPMGGGGGGQSASLYDSCGAYATTNVVANVKLYQNRYATKPNQSSGSNNNNHQGNDYQSTGMYSAPPSAHYGCLEPKQQQQQQQPNLMTTSTASTAILTNSPAKVKKINITENKMDQLEGKSERTNPFNQQQQLLLASNALKQGLGAYANTTLAAQMASGGGAGTLRRQRQPKTLYKSENNILGKSGLRQNTMNASVGAPSNGQMDFLTGGPPSEGGDFSGLGLCNSTNQLLNDWASSASIAAPGDYHFGSKQPSKQHLYVKAKDGTWSAVSSDAYQSFKHQQQHHPFLAGSGDNTKSLASVNSLAGDSKFLSSFGSSANV.

For Research Use Only | Not For Clinical Use.

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