Rabbit Anti-RPS3 Antibody (MO-DKB-00726W)


Cat: MO-DKB-00726W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Bovine (Bos taurus), Dog (Canis lupus familiaris), Chicken (Gallus gallus), Primat, Rhesus (Macaca mulatta), Frog (Xenopus), Zebrafish (Danio rerio)
ImmunogenA recombinant protein containing sequences in the central region of human RPS3.
EpitopeThe epitope is in the Center of RPS3.
FormatLiquid or Lyophilized
BufferPBS, pH 7, 20% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAffinity purified

Application Information

ApplicationWB, IF, IHC, IHC-P, IP
Application NotesWestern Blot 1:500-1:3000
Immunocytochemistry/Immunofluorescence 1:100-1:1000
Immunohistochemistry 1:100-1:1000
Immunohistochemistry-Paraffin 1:100-1:1000
Immunoprecipitation 1:10-1:500

Target

IntroductionRibosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Product OverviewThis product is a Rabbit antibody against the Center of the RPS3. It can be used for RPS3 detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation.
Alternative NamesRibosomal Protein S3; Small Ribosomal Subunit Protein US3; IMR-90 Ribosomal Protein S3; 40S Ribosomal Protein S3; EC 4.2.99.18; S3;
Gene ID6188
UniProt IDP23396
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For Research Use Only | Not For Clinical Use.
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