Mouse Anti-sim2 Antibody (CBMOAB-05398FYB)

Cat: CBMOAB-05398FYB

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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-05398FYB	Monoclonal	Zebrafish (Danio rerio), Frog (Xenopus laevis)	WB, ELISA	MO05398FYB		100 µg	Inquiry
Protein Refseq: The length of the protein is 585 amino acids long. The sequence is show below: MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPDGLGEAWGQSARVSPLDIMAKDLGSHLLQTLDGFVFVVASDGKILYISETASVHLGLSQVELTGNSIFEYIHPSDHDEMSAVLSTHQPLHTHFLQELELERSFFLRMKCVLAKRNAGLTSGGYKVIHCSGYLQVRPLVLDVSVCQSCCQLVAVAHSLPPSGLTEIKLHSNMFMFRASLDLKLIFLDSRVSELTGHEPQDLIEKTLYHHVHGCDVFHLRFAHHLLLVKGQVTTRYYRLLSKRGGWVWVQSCATIVHNSRSSRPHCIVSVNYVLTDVEYRELQLSEDQRRCRLSYKDCLTAEQNTHTHTHTQMKSKAAKTRSRTRAAPYTQVSLCRVDKAERVLWSSSPPSCQQQSPGPLTPSGPQPCAYTHTLSPRRQGSSAPQTSRDAPWSCSAAENKPAAGCTYSGVLRGGACKEESGLIRRLQPDTQRRRLTESPYEDRNTHRAPGPADGDGRRLLLGVRVPAQGPLVSLNLHHCLLSKHSSVPPAPYTHRGEQRTPYLQQSPSLASAGPRGPHYISTSVIISGER.
MO-AB-07630H	Monoclonal	Frog (Xenopus laevis)	WB, ELISA	MO07630C		100 µg	Inquiry
Protein Refseq: The length of the protein is 760 amino acids long. The sequence is show below: MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPDGLGDAWGHPSRIGPLDNVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHQPLHPHLLQEYEIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDISLYDSCYQIVGLVAVGQSLPPSAITEIKLHSNMFMFRASLDLKLIFLDSRVAELTGYEPQDLIEKTLYHHVHGCDVFHLRYAHHLLLVKGQVTTKYYRLLSKNGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDVEYKELQLSLEQVTVSKVPFSCRTPMTTSQEARKPIKVKTGKVKSKPRTNPYPQTYTSFIGDKRDCSQYGSWKGTPTMNTATNQEQSNHSENSELLYTPTYSLPFSYHYGHFPMDSHVLSSKKQVMPSRYGQPQSSSPCEVARFFFSTLQSSGECHWHYANSVVPSSPPKNIHEQSVTQVRHNLAHNYEAPKKFSALDSPPDGFTDCSMSRSSPRYKDELYHSSPMKTNKSENRAAPPYHGVKEENKLSFSRYQQEKTFANEKHFSNSLSNSVLQKSECLHAKTIEQLSHLLPRPVVYEQTRRLCMKEPRYSHPNFHHSGYNELENDRTNSRFAHHNSEHEHFKPGGQVPYVPLNYHHVLSKHGTCQTSPCAGTEHGTEHYGYGSEEVNAFVYKNQRQSSVSSPETHRETSVPHYIGTSVIITNER.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Zebrafish (Danio rerio), Frog (Xenopus laevis)
Clone	MO05398FYB
Specificity	This antibody binds to Zebrafish sim2.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Nucleus; Other locations

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Product Overview	Mouse Anti-Zebrafish sim2 Antibody is a mouse antibody against sim2. It can be used for sim2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	Single-minded homolog 2; Drosophila; Single-minded protein; sim
UniProt ID	Q8UVV3
Protein Refseq	The length of the protein is 585 amino acids long. The sequence is show below: MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPDGLGEAWGQSARVSPLDIMAKDLGSHLLQTLDGFVFVVASDGKILYISETASVHLGLSQVELTGNSIFEYIHPSDHDEMSAVLSTHQPLHTHFLQELELERSFFLRMKCVLAKRNAGLTSGGYKVIHCSGYLQVRPLVLDVSVCQSCCQLVAVAHSLPPSGLTEIKLHSNMFMFRASLDLKLIFLDSRVSELTGHEPQDLIEKTLYHHVHGCDVFHLRFAHHLLLVKGQVTTRYYRLLSKRGGWVWVQSCATIVHNSRSSRPHCIVSVNYVLTDVEYRELQLSEDQRRCRLSYKDCLTAEQNTHTHTHTQMKSKAAKTRSRTRAAPYTQVSLCRVDKAERVLWSSSPPSCQQQSPGPLTPSGPQPCAYTHTLSPRRQGSSAPQTSRDAPWSCSAAENKPAAGCTYSGVLRGGACKEESGLIRRLQPDTQRRRLTESPYEDRNTHRAPGPADGDGRRLLLGVRVPAQGPLVSLNLHHCLLSKHSSVPPAPYTHRGEQRTPYLQQSPSLASAGPRGPHYISTSVIISGER.

For Research Use Only | Not For Clinical Use.

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