Mouse Anti-SLC7A11 Antibody (MO-AB-17696Y)


Cat: MO-AB-17696Y
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MO-AB-17696Y Monoclonal Sheep (Ovis aries), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Marmoset, Pig (Sus scrofa) WB, ELISA MO17696Y 100 µg
MO-AB-20497R Monoclonal Cattle (Bos taurus) WB, ELISA MO20497R 100 µg
MO-AB-26307W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO26307W 100 µg
MO-AB-30202R Monoclonal Pig (Sus scrofa) WB, ELISA MO30202R 100 µg
MO-AB-33414W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO33414W 100 µg
MO-AB-64771W Monoclonal Marmoset WB, ELISA MO64771W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivitySheep (Ovis aries), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Marmoset, Pig (Sus scrofa)
CloneMO17696Y
SpecificityThis antibody binds to Sheep SLC7A11.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. (From NCBI)
Product OverviewThis product is a mouse antibody against SLC7A11. It can be used for SLC7A11 detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesAnionic amino acid transporter light chain xCT; SLC7A11
UniProt IDH2EUS8
Protein RefseqThe length of the protein is 503 amino acids long. The sequence is show below: MVRKPVVSTISNGAYLQGSVNGRLPAPGGKEPPGQEKVVLKKKITLLRGISIIIGTIIGAGIFISPKGVLQNTGSVGLSLVVWSVCGVLSLFGALSYAELGTSIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIHCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQTQYFKDAFSGRDASIMGLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMTVVTVGYVLTNVAYFTTISAEELMLSNAVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHIRKHTPLPAVIVLHPLTMIMLFSGDLYSLLNFLSFARWLFIGLAVAGLIYLRYKRPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGFIITLTGIPAYYLFIIWDKKPKWFRRMSDIITRTLQIILEVVPEEDCHKL.
For Research Use Only | Not For Clinical Use.
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