Rabbit Anti-SMC3 Antibody (MO-DKB-00413W)


Cat: MO-DKB-00413W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), C. elegans (Caenorhabditis elegans), Bovine (Bos taurus), Primat
ImmunogenThe region between residue 1175 and the structure of human chromosome 3 maintains the C-terminus, using the number given in entry NP_005436.1.
EpitopeThe epitope is in the AA 1175-1217 of SMC3.
FormatLiquid or Lyophilized
BufferTris-Citrate/Phosphate (pH 7.0-8.0)
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAffinity purified

Application Information

ApplicationWB, IHC, IHC-P, IP
Application NotesWestern Blot 1:10000-1:25000
Immunohistochemistry
Immunohistochemistry-Paraffin 1:100-1:500
Immunoprecipitation 2-10 ul/mg

Target

IntroductionThis gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008]
Product OverviewThis product is a Rabbit antibody against the AA 1175-1217 of the SMC3. It can be used for SMC3 detection in Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation.
Alternative NamesStructural Maintenance Of Chromosomes 3; Basement Membrane-Associated Chondroitin Proteoglycan; Chondroitin Sulfate Proteoglycan 6 (Bamacan); Chromosome-Associated Polypeptide; SMC Protein 3; SMC3L1; CSPG6; HCAP; BAM;
Gene ID9126
UniProt IDQ9UQE7
For Research Use Only | Not For Clinical Use.
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