Rabbit Anti-SNAP25 Antibody (MOFAB-426W)


Cat: MOFAB-426W
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Specifications

Host speciesRabbit
Species ReactivityHuman, Rat, Mouse, Vertebrates, Invertebrates, Zebrafish
SpecificityDetection of splice variants SNAP 25A and B. Identify botulinum neurotoxin A and E cleavage products.
ImmunogenRecombinant protein corresponding to AA 1 to 206 from rat SNAP25B (UniProt ID: P60881-1)
EpitopeAA 20-40
FormatLiquid or Lyophilized
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationWB, IP, ICC, IHC-P
Application NotesThe optimal dilution should be determined by the end user.

Target

IntroductionSynaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Product OverviewThis product is a Rabbit antibody against the AA 20-40 of the SNAP25. It can be used for SNAP25 detection in Western Blot, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry-Paraffin.
Alternative NamesSynaptosome Associated Protein 25; Resistance To Inhibitors Of Cholinesterase 4 Homolog; Synaptosomal-Associated Protein, 25kDa; SNAP-25; SNAP; SUP; Synaptosomal-Associated 25 KDa Protein; Synaptosome Associated Protein 25kDa; Synaptosomal-Associated Protein 25; SNAP 25
Gene ID6616
UniProt IDP60880
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For Research Use Only | Not For Clinical Use.
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