Mouse Anti-Sugar beet cox3 Antibody (MO-AB-30267H)
Cat: MO-AB-30267H
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Sugar beet (Beta vulgaris) |
Clone | MO30267C |
Specificity | This antibody binds to Sugar beet cox3. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Other locations; Mitochondrion |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of COX2 and heme A of COX1 to the active site in COX1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix (Probable). COX3 is a catalytic core subunit (PubMed:30598554). |
Product Overview | This product is a mouse antibody against cox3. It can be used for cox3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Cytochrome c oxidase subunit 3; cox3 |
UniProt ID | Q9MF54 |
Protein Refseq | The length of the protein is 265 amino acids long. The sequence is show below: MIESQRHSFHLVDPSPWPISGSLGALATTVGGVMYMHSFQGGATLLSLGLIFILYTMFVWWRDVLRESTLEGHHTKVVQLGLRYGFILFIVSEVMFFFAFFWAFFHSSLAPAVEIGGIWPPKGIWVLDPWEIPFLNTLILLSSGAAVTWAHHAILAGKQKRAVYALVATVLLALVFTGFQGMEYYEAPFTISDSIYGSTFFLATGFHGFHVIIGTLFLIICGIRQYFGHLTKEHHVGFEAAAWYWHFVDVVWLFLFVSIYWWGGI. |
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For Research Use Only | Not For Clinical Use.
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