Name: AibGenesis™ Mouse Anti-TASOR Antibody (CBMOAB-60339FYC)
SKU: CBMOAB-60339FYC
Rating: 5 (1 reviews)

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-60339FYC	Monoclonal	Rhesus (Macaca mulatta), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis)	WB, ELISA	MO60339FYC		100 µg	Inquiry
Protein Refseq: The length of the protein is 1515 amino acids long. The sequence is show below: MATAVETEASQPTDASCESGGGGDDEMKQALPELESSPQNGGGGGGLNIAEPGGGAGPEETAGAEAAQSFSHEQPQDSSEAGAAALLRGPEEPERPLRRSFQIPRKSREKKALFQPLTPGSREFEDVVNILHSSYLEPTSVTNFNYRRACLIHNELLEKEFTEKRRELKFDGRLDKELSESYAFLMVDRYQVQSICEKGLHVGQSKITILGSPSMGVYLSRYADLLQANPLDTGAMGDVVIFKIMKGKIKSIYDPMGVKSLESMLNKSALDPTPKHECHVSKNANRITSLLAYRAYELTQYYFYEYGFDELRRRPRHVCPYAVVSFTYKDDIQTPKFVPSSRSNSFNADRNVDKYNYTLWKGQLLNKGKLLCYISLRSATRAFLPIKLPEKLDVETVMSIDHLKQKIPPALFYKETYLGPNEVLKNGMYCSLYEVVEKTRIGSNMESLLQKLDREKLVLVKPLGDRGYLFLLSPYQMVPPYEYQTAKSRVLHALFLFQEPRSIVTSQKGSTNAAPKERHESMPDVLKIAQFLQFSLIQCRKEFKNISTINFHSVVEKYVSEFFKRGFGSGKREFIMFPYDSRLDDKKFLYSAPRNKSHIDTCLHAYIFRPEMYQLPICKLKELFEENRKLQQFSPLSDYEGQEEEVNGTKMKFGKRNNSRGETILSGKQRSSHSLDYDKDRVKELINLIQCRKKNVGGDSDTEDMRSKTVLKRKLEDLPENMRKLAKTSNLSENCHLFEESPQPIGSLGHDADLRRQQQDTCNSGIADIHRLFNWLSETLANARHSDASLTDTVNKALGLSTDDAYEELRQKHEYELNSNPDKKEYEQPTCAKIENAQFKGTQSLLLEVDATSKYSVAISTTEVGTDHKLHLKEDPNLISMNNFEDCSLCPSVPIEHGFRRQQSKSNNVEETEIHWKLIPITGGNARSPEDQLGKHGEKQTPGMKSPEEQLVCVPPQEAFPNDPRVINRQRSSDYQFPSSPFTDTLKGTTEDDVLTGQVEEQCVPAAEAEPPAVSETTERTVLGEYNLFSRKIEEILKEKNVSYVSRVSTPIFTTQEKMKRLSEFIYSKTSKAGVQEFVDGLHEKLNTIIIKASAKGGNLPPVSPNDSGAKIASNLLERHVIPVSSSDFNNKHLLEPLCSDPLKDTNSNEQHSTSTLSLTEVEMNQPQHATELTVTSDHTVPGDMAREPVEETTKSPSDVNISAQPALSNFISQLEPEVFNSLVKIMKDVQKNTVKFYIHEEEESVLCKEIKEYLIKLGNTECHPEQFLERRSKLDKLLIIIQNEDIAGFIHKIPGLVTLKKLPCVSFAGVDSLDDVKNHTYNELFVSGGFIVSDESILNPEVVTIENLKNFLTFLEELSTPEGKWQWKVHCKFQKKLKELGRLNAKALSLLTLLNVYQKKHLVEILSYHNCDSQTRNAPELDCLIRLQAQNIQQRHIVFLTEKTIKMLSSYTDNGIVVATAEDFMQNFKNLVGYHNSITEENLPQLGANENLESQSDAVLTLTPLELGVGISQH.
MO-AB-08267H	Monoclonal	Frog (Xenopus laevis)	WB, ELISA	MO08267C		100 µg	Inquiry
Protein Refseq: The length of the protein is 1094 amino acids long. The sequence is show below: MPESHEFMPEFLTFVPALHFALHKSQSDTSADFNDVVEKHSRVYLKRRAEIPHKSKEYILKPYDSRLDYKKSLYVAPRNKGHIESALRSYIFGSEAYTISVDKAKEMVKENQRFQQFSPVSDYEPVEDDHDSSKYNKKAPVSYTETKSEKASENTDWDIDKINGLINLIQKKKQSKPETDEPSSVGVKRKRERHSENVWKPRKCEENFHHDNEPGESAQSLISSMGGQDTDLRQETPEPLTSEYLKMLLEKLADSCMDPALVQSLKSLKQNTTEELPAQKLENVSLAAHDTEREAVRQVYEDQTSDYQENTTSFSEEAQEAEGSHSDPLVPMEENILDPPLESASPCLSHTADNICPMQGPNSLDLEMHWKLIPIAGEEARTPEDHVGTLRDEKTPELNLTKEQLVYVSTEDALPNDPRAGHKRRVSRYSPLRETGRRRPRHDGDHCRSRTAPSRTERNMLQSKHCHNGLIENTVLEIYNTFSEQLHDVLKQRDVPYMVPATPPLLSSDDRVLKLSDCLYEQASDICVQQYVDDLHIKLDNVVAIHINSCAISRTLTPVTEIMASPGVHPFHPTQTLTEYPHAHHHLHCDVREEHPFSADHVDKVGEENAANGNEPSHHSRDLSQETPEISAPNVTDLSAPHLAISNLINQINPEVFNNLVKIITHVNKNSVKFYIHSEEENTICQNIKEYLLKLGNAECRPEKFLESKTKVDKLLIIIQNEDIPNCIHRVPALVLLKRLPSVSFAGVDSLDDLKNHTYNEIFVSGGFIVSDESVLNPETVSADELKKFLLFLEEINSPDANWQWKVHYKFHKRLKELGRVNANALNILTLLTTYQKKNLVEILSYHLSCDPQNQPAPQLECLIKLQVQYMKQRHVIFLTEKDAARFPDYCDNGIVVTRMVDFMDNFSSLIGHHSSNNEEHRLSQLTDEGDETGNYAPGEADVKEEEDMSLDSEDDTPPIEVCSDSRQPESPNQNISSALVDKDQTESPSTINQSKTPTLDELQPITPVSVAGSTTGENSVSTGDELGNTTQDYNRDVNLSHQFSHFNVLTHQTFLGSMYPALSNPAPAEICFMNSCSQQTEPEKSHNSECKQK.
MO-AB-13969W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO13969W		100 µg	Inquiry
Protein Refseq: The length of the protein is 1512 amino acids long. The sequence is show below: MATAVETEACQPTDASWESGGGGDDEMKQALPELESSPQNGGGGGLNIAEPSGGAGPEENAGAEAAQSLSHEQPQDSSEAGAAALPRGPEEPERPVRRSFQIPRKSREKKALFQPLTPGSREFEDVVNILHSSYLEPTSVTNFNYRRACLVHNELLEKEFTEKRRELKFDGRLDKELSESYAFLMVDRYQVQTICEKGLHVGQSKITILGSPSMGVYVSRYADLLQANPLDTGATGDVVIFKIMKGKIKSIYDPMGVKSLESMLNKSALDPTPKHECHVSKNANRITSLLAYRAYELTQYYFYEYGFDELRRRPRHVCPYAVVSFTYKDDIQTPKFVPSSRSNSFNTDRNIDKYNYTLWKGQLLNKGKLLCYISLRSATRAFLPIKLPEKLDVETVMSIDHLKQKIPPALFYKETYLGPNEVLKNGMYCSLYEVVEKTRIGSNMESLLQKLDREKLVLVKPLGDRGYLFLLSPYQMVPPYEYQTAKSRVLHALFLFQEPRSIVTSQKGSTNAAPQERHESMPDVLKIAQFLQFSLIQCRKEFKNISAINFHSVVEKYVSEFFKRGFGSGKREFIMFPYDSRLDDKKFLYSAPRNKSHIDTCLHAYIFRPEVYQLPICKLKELFEENRKLQQFSPLSDYEGQEEEMNGTKMKFGKRNNSRGEAIISGKQRSSHSLDYDKDRVKELINLIQCRKKSVGGDSDTEDMRSKTVLKRKLEDLPENMRKLAKTSNLSENCHLYEESPQPIGSLGHDADLRRQQQDTCNSGIADIHRLFNWLSETLANARHSDASLTDTVNKALGLNTDDAYEELRQKHEYELNSTPDKKDYEQPTCAKVENAQFKGTQSLLLEVDATSKYSVAISTSEVGTDHKLHLKEDPNLISVNNFEDCSLCPSVPIEHGFRRQQSKSNNVEETEIHWKLIPITGGNARSPEDQLGKHGEKQTPGMKSPEEQLVCVPPQEAFPNDPRVINRQRSSDYQFPSSPFTDTLKGTTEDDVLTGQVEEQCVPAAEAEPPAVSETTERTVLGEYSLFSRKIEEILKQKNVSYVSRVSTPIFSTQEKMKRLSEFIYSKTSKAGVQEFVDGLHEKLNTIIIKASAKGGNLPPVSPNDSGAKIASNPLERHVLPVSSSDFNNKHLLEPLCSDPLKDTNSDEQHSTSALTEVEMNQPQHATELMVTSDHIVPGDMAREPVEETTKSPSDVNISAQPALSNFISQLEPEVFNSLVKIMKDVQKNTVKFYIHEEEESVLCKEIKEYLIKLGNTECHPEQFLERRSKLDKLLIIIQNEDIAGFIHKIPGLVTLKKLPCVSFAGVDSLDDVKNHTYNELFVSGGFIVSDESILNPEVVTIENLKSFLTFLEELSTPEGKWQWKVHCKFQKKLKELGRLNAKALSLLTLLNVYQKKHLVEILSYHNCDSQTRNAPELDCLIRLQAQNIQQRHIVFLTEKNIKMLSSYTDNGIVVATAEDFMQNFKNLVGYHNSITEENLPQLGANENLESQSDAVLTLTPLELGVGISQH.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Rhesus (Macaca mulatta), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis)
Clone	MO60339FYC
Specificity	This antibody binds to Rhesus TASOR.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Nucleus; Other locations

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression (PubMed:26022416, PubMed:28581500). The HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3, as well as MORC2 (PubMed:26022416, PubMed:28581500). Also represses L1 retrotransposons in collaboration with MORC2 and, probably, SETDB1, the silencing is dependent of repressive epigenetic modifications, such as H3K9me3 mark. Silencing events often occur within introns of transcriptionally active genes, and lead to the down-regulation of host gene expression (PubMed:29211708). The HUSH complex is also involved in the silencing of unintegrated retroviral DNA by being recruited by ZNF638: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed. (From uniprot, under CC BY 4.0)
Product Overview	Mouse Anti-Rhesus TASOR Antibody is a mouse antibody against TASOR. It can be used for TASOR detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	Retinoblastoma-associated protein 140 isoform a; TASOR
UniProt ID	H9Z6W8
Protein Refseq	The length of the protein is 1515 amino acids long. The sequence is show below: MATAVETEASQPTDASCESGGGGDDEMKQALPELESSPQNGGGGGGLNIAEPGGGAGPEETAGAEAAQSFSHEQPQDSSEAGAAALLRGPEEPERPLRRSFQIPRKSREKKALFQPLTPGSREFEDVVNILHSSYLEPTSVTNFNYRRACLIHNELLEKEFTEKRRELKFDGRLDKELSESYAFLMVDRYQVQSICEKGLHVGQSKITILGSPSMGVYLSRYADLLQANPLDTGAMGDVVIFKIMKGKIKSIYDPMGVKSLESMLNKSALDPTPKHECHVSKNANRITSLLAYRAYELTQYYFYEYGFDELRRRPRHVCPYAVVSFTYKDDIQTPKFVPSSRSNSFNADRNVDKYNYTLWKGQLLNKGKLLCYISLRSATRAFLPIKLPEKLDVETVMSIDHLKQKIPPALFYKETYLGPNEVLKNGMYCSLYEVVEKTRIGSNMESLLQKLDREKLVLVKPLGDRGYLFLLSPYQMVPPYEYQTAKSRVLHALFLFQEPRSIVTSQKGSTNAAPKERHESMPDVLKIAQFLQFSLIQCRKEFKNISTINFHSVVEKYVSEFFKRGFGSGKREFIMFPYDSRLDDKKFLYSAPRNKSHIDTCLHAYIFRPEMYQLPICKLKELFEENRKLQQFSPLSDYEGQEEEVNGTKMKFGKRNNSRGETILSGKQRSSHSLDYDKDRVKELINLIQCRKKNVGGDSDTEDMRSKTVLKRKLEDLPENMRKLAKTSNLSENCHLFEESPQPIGSLGHDADLRRQQQDTCNSGIADIHRLFNWLSETLANARHSDASLTDTVNKALGLSTDDAYEELRQKHEYELNSNPDKKEYEQPTCAKIENAQFKGTQSLLLEVDATSKYSVAISTTEVGTDHKLHLKEDPNLISMNNFEDCSLCPSVPIEHGFRRQQSKSNNVEETEIHWKLIPITGGNARSPEDQLGKHGEKQTPGMKSPEEQLVCVPPQEAFPNDPRVINRQRSSDYQFPSSPFTDTLKGTTEDDVLTGQVEEQCVPAAEAEPPAVSETTERTVLGEYNLFSRKIEEILKEKNVSYVSRVSTPIFTTQEKMKRLSEFIYSKTSKAGVQEFVDGLHEKLNTIIIKASAKGGNLPPVSPNDSGAKIASNLLERHVIPVSSSDFNNKHLLEPLCSDPLKDTNSNEQHSTSTLSLTEVEMNQPQHATELTVTSDHTVPGDMAREPVEETTKSPSDVNISAQPALSNFISQLEPEVFNSLVKIMKDVQKNTVKFYIHEEEESVLCKEIKEYLIKLGNTECHPEQFLERRSKLDKLLIIIQNEDIAGFIHKIPGLVTLKKLPCVSFAGVDSLDDVKNHTYNELFVSGGFIVSDESILNPEVVTIENLKNFLTFLEELSTPEGKWQWKVHCKFQKKLKELGRLNAKALSLLTLLNVYQKKHLVEILSYHNCDSQTRNAPELDCLIRLQAQNIQQRHIVFLTEKTIKMLSSYTDNGIVVATAEDFMQNFKNLVGYHNSITEENLPQLGANENLESQSDAVLTLTPLELGVGISQH.