Mouse Anti-Tfiia-S Antibody (CBMOAB-32936FYA)
Cat: CBMOAB-32936FYA
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-32936FYA | Monoclonal | Fruit fly (Drosophila melanogaster), A. thaliana (Arabidopsis thaliana) | WB, ELISA | MO32936FYA | 100 µg | ||
| CBMOAB-44951FYC | Monoclonal | A. thaliana (Arabidopsis thaliana) | WB, ELISA | MO44951FC | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster), A. thaliana (Arabidopsis thaliana) |
| Clone | MO32936FYA |
| Specificity | This antibody binds to fruit fly Tfiia-S. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation (PubMed:7958898). TFIIA in a complex with TBP mediates transcriptional activity (PubMed:7958898). Part of a rhi-dependent transcription machinery that enables the generation of piRNA precursors from heterochromatin while maintaining the suppression of transposon-encoded promoters and enhancers (PubMed:28847004). Forms a complex with Moonshiner/CG12721 and Trf2 which recruit transcriptional machinery to heterochromatin to initiate the bidirectional transcription of piRNA clusters, by interacting with the RDC (rhi, del and cuff) complex that binds to repressive H3K9me3 marks in the chromatin (PubMed:28847004). This mechanism allows transcription to occur in piRNA clusters despite the lack of proper promoter elements and in the presence of the repressive H3K9me3 mark (PubMed:28847004). |
| Product Overview | Mouse Anti-D. melanogaster Tfiia-S Antibody is a mouse antibody against Tfiia-S. It can be used for Tfiia-S detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Transcription initiation factor IIA subunit 2; General transcription factor IIA subunit 2; TFIIA p14 subunit; TFIIA-14; Transcription initiation factor IIA gamma chain; TFIIA-gamma; dTFIIA-S; TfIIA-S |
| UniProt ID | P52656 |
| Protein Refseq | The length of the protein is 106 amino acids long. The sequence is show below: MSYQLYRNTTLGNTLQESLDELIQYGQITPGLAFKVLLQFDKSINNALNQRVKARVTFKAGKLNTYRFCDNVWTLMLNDVEFREVHEIVKVDKVKIVACDGKSGEF. |
For Research Use Only | Not For Clinical Use.
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