Mouse Anti-unc-10 Antibody (AA 1-144)
Cat: MO-NAB-00586W
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- Product List
- Specifications
- Application Information
- Target
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | C. elegans (Caenorhabditis elegans) |
| Clone | NW0508 |
| Specificity | This antibody is binds to C. elegans unc-10. |
| Immunogen | Recombinant His6 labeled UNC-10 (aa 1-144) fusion protein. |
| Epitope | The epitope is in the AA 1-144 of unc-10 |
| Format | Liquid or Lyophilized |
| Buffer | Supernatant |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Application Information
| Application | IF |
Target
| Introduction | Regulates the efficiency of a post-docking step of the release pathway. Acts after vesicle docking likely via regulating priming. May regulate the conformational changes in syntaxin. Binding of vesicles via rab-3[GTP] to Rim may signal the presence of a docked synaptic vesicle. Rim may then signal to unc-13 to change the conformation of syntaxin from the closed to the open state. Syntaxin could then engage synaptobrevin on the docked vesicle to form SNARE complexes and to prime the vesicle for release. Not required for the development or the structural organization of synapses. May play a role in regulating entry into the dauer state (PubMed:30460068). (From uniprot, under CC BY 4.0) |
| Product Overview | This product is a Mouse antibody against the AA 1-144 of the unc-10. It can be used for unc-10 detection in Immunofluorescence. |
| Alternative Names | Rab-3-interacting molecule unc-10; Rim; Uncoordinated protein 10; unc-10 |
| Gene ID | 180990 |
| UniProt ID | Q22366 |
For Research Use Only | Not For Clinical Use.
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