Mouse Anti-VEGFA Antibody (MO-AB-04736Y)


Cat: MO-AB-04736Y
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MO-AB-04736Y Monoclonal Chicken (Gallus gallus), Cat (Felis catus), Cattle (Bos taurus), Dog (Canis lupus familiaris), Dog, Mouse, Rat, Frog (Xenopus laevis), Goat (Capra hircus), Guinea pig (Cavia porcellus), Horse (Equus caballus), Ovis aries, Sheep, Pig, Rabbit, Rat (Rattus norvegicus), Sheep (Ovis aries) WB, ELISA MO04736Y 100 µg
MO-AB-08790W Monoclonal Cat (Felis catus) WB, ELISA MO08790W 100 µg
MO-AB-09029H Monoclonal Frog (Xenopus laevis) WB, ELISA MO09029C 100 µg
MO-AB-18211Y Monoclonal Sheep (Ovis aries) WB, ELISA MO18211Y 100 µg
MO-AB-22770R Monoclonal Cattle (Bos taurus) WB, ELISA MO22770R 100 µg
MO-AB-29970H Monoclonal Rat (Rattus norvegicus) WB, ELISA MO29970C 100 µg
MO-AB-34012W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO34012W 100 µg
MO-AB-38398W Monoclonal Goat (Capra hircus) WB, ELISA MO38398W 100 µg
MO-AB-42838W Monoclonal Guinea pig (Cavia porcellus) WB, ELISA MO42838W 100 µg
MO-AB-47060W Monoclonal Horse (Equus caballus) WB, ELISA MO47060W 100 µg
MOFY-0722-FY11 Monoclonal Pig WB, IHC, ICC, IP 100 µg
MOFY-0622-FY186 Polyclonal Rabbit WB, IHC, ICC, IP 100 µg
MOFY-0622-FY84 Polyclonal Ovis aries, Sheep WB, IHC, ICC, IP 100 µg
MOFY-0722-FY222 Polyclonal Dog, Mouse, Rat WB, IHC, ICC, IP 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityChicken (Gallus gallus), Cat (Felis catus), Cattle (Bos taurus), Dog (Canis lupus familiaris), Dog, Mouse, Rat, Frog (Xenopus laevis), Goat (Capra hircus), Guinea pig (Cavia porcellus), Horse (Equus caballus), Ovis aries, Sheep, Pig, Rabbit, Rat (Rattus norvegicus), Sheep (Ovis aries)
CloneMO04736Y
SpecificityThis antibody binds to Chicken VEGFA.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 2015]
Product OverviewThis product is a mouse antibody against VEGFA. It can be used for VEGFA detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesVascular endothelial growth factor A; VEGFA
UniProt IDF1NAQ1
Protein RefseqThe length of the protein is 215 amino acids long. The sequence is show below: MNFLLTWIHWGLAALLYLQSAELSKAAPALGGERKPNEVIKFLEVYERSFCRTIETLVDIFQEYPDEVEYIFRPSCVPLMRCAGCCGDEGLECVPVDVYNVTMEIARIKPHQSQHIAHMSFLQHSKCDCRPKKDVKNKQEKKSKRGKGKGQKRKRKKGRYKPPSFHCEPCSERRKHLFVQDPQTCKCSCKFTDSRCKSRQLELNERTCRCEKPRR.
For Research Use Only | Not For Clinical Use.
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