Cat: CBMOAB-00196CR
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Yeast |
| Clone | MO00196CR |
| Specificity | This antibody binds to Yeast AIR1. |
| Format | Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Component of the TRAMP (TRF4) and TRAMP5 complexes which have a poly(A) RNA polymerase activity and are involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information. Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates like cryptic transcripts generated by RNA polymerase II and III, or hypomethylated pre-tRNAi-Met. Both complexes polyadenylate RNA processing and degradation intermediates of snRNAs, snoRNAs and mRNAs that accumulate in strains lacking a functional exosome. AIR1 also inhibits the methylation of NPL3 mediated by HMT1 through its interaction with HMT1. |
| Product Overview | Mouse Anti-Yeast AIR1 (clone MO00196CR) Antibody (CBMOAB-00196CR) is a mouse antibody against AIR1. It can be used for AIR1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Protein AIR1; Arginine methyltransferase-interacting RING finger protein 1; AIR1; YIL079C |
| UniProt ID | P40507 |
| Protein Refseq | The length of the protein is 360 amino acids long. The sequence is show below: MSTLLSEVESIDTLPYVKDTTPTGSDSSSFNKLLAPSIEDVDANPEELRTLRGQGRYFGITDYDSNGAIMEAEPKCNNCSQRGHLKRNCPHVICTYCGFMDDHYSQHCPKAIICTNCNANGHYKSQCPHKWKKVFCTLCNSKRHSRERCPSIWRSYLLKTKDANQGDFDFQTVFCYNCGNAGHFGDDCAERRSSRVPNTDGSAFCGDNLATKFKQHYFNQLKDYKREASQRQHFDNEHEFNLLDYEYNDDAYDLPGSRTYRDKMKWKGKVQSTRNKNSSNNRYESSNNRKKKSPFSAQNYKVTKNKRVQTHPLDFPRSSQNNRTNDYSSQFSYNRDDFPKGPKNKRGRSSSNKSQRNGRY. |
See other products for " AIR1 "
| CBMOAB-1958FYC | Mouse Anti-Arabidopsis AIR1 Antibody (CBMOAB-1958FYC) |
| CBMOAB-1957FYC | Mouse Anti-Arabidopsis AIR1 Antibody (CBMOAB-1957FYC) |
| CBMOAB-00452HCB | Mouse Anti-C. elegans AIR1 Antibody (CBMOAB-00452HCB) |
For Research Use Only | Not For Clinical Use.