Mouse Anti-Yeast DAD1 Antibody (CBMOAB-00943CR)


Cat: CBMOAB-00943CR
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityYeast
CloneMO00943CR
SpecificityThis antibody binds to Yeast DAD1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Cytoskeleton; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionComponent of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore. The DASH ring complex may both stabilize microtubules during chromosome attachment in anaphase A, and allow the chromosome to remain attached to the depolymerizing microtubule in anaphase B. Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached ring to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids.
Product OverviewMouse Anti-Yeast DAD1 Antibody is a mouse antibody against DAD1. It can be used for DAD1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesDASH complex subunit DAD1; DUO1 and DAM1-interacting protein 1; Outer kinetochore protein DAD1; DAD1; YDR016C
UniProt IDQ12248
Protein RefseqThe length of the protein is 94 amino acids long. The sequence is show below: MMASTSNDEEKLISTTDKYFIEQRNIVLQEINETMNSILNGLNGLNISLESSIAVGREFQSVSDLWKTLYDGLESLSDEAPIDEQPTLSQSKTK.
For Research Use Only | Not For Clinical Use.
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