AibGenesis™ Mouse Anti-zbtb48 Antibody (CBMOAB-16700FYB)


Cat: CBMOAB-16700FYB

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Lot Number

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  • Specifications
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-16700FYB Monoclonal Zebrafish (Danio rerio), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset WB, ELISA MO16700FYB 100 µg
MO-AB-09449H Monoclonal Frog (Xenopus laevis) WB, ELISA MO09449C 100 µg
MO-AB-14890W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO14890W 100 µg
MO-AB-68125W Monoclonal Marmoset WB, ELISA MO68125W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityZebrafish (Danio rerio), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset
CloneMO16700FYB
SpecificityThis antibody binds to Zebrafish zbtb48.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionTelomere-binding protein that acts as a regulator of telomere length (PubMed:28500257, PubMed:28082411). Directly binds the telomeric double-stranded 5-TTAGGG-3 repeat (PubMed:28500257, PubMed:28082411). Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres (PubMed:28082411). Also acts as a transcription regulator that binds to promoter regions (PubMed:7969177, PubMed:24382891, PubMed:28500257). Regulates expression of a small subset of genes, including MTFP1 (PubMed:28500257). Regulates expression the J and/or S elements in MHC II promoter (PubMed:7969177). Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A (PubMed:24382891). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-Zebrafish zbtb48 Antibody is a mouse antibody against zbtb48. It can be used for zbtb48 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Nameszbtb48; Zinc Finger And BTB Domain Containing 48
UniProt IDE7FDZ5
Protein RefseqThe length of the protein is 760 amino acids long.
The sequence is show below: MEKLAEGSSHAQRVLSLLNKQRAFGHFCDAMLCTASGQVHLAHRNVLACFSQLFQEPTSKTPSIKFDLPLECPDDGLELLLNFFYTGDLQLDDSNLEKVQNAASGLSVPVFLIPCQGIKTPDLNEGDPSKPLLSEPQPDQTPNKKTRSGQRTKNKADAFKLSTASDDEPPALKSTTVTRSGRRVKGPSRLVGESQISVVTRLGVGRRKASFVEDKEQETGATEDGDHPRHEDASETTQTTEVDISVDDQNDDDDDVEDAANNDDDSDRGGSVDIIIEGTDEEYVPHDSPCSSTKTPRGKRKEKSSNKKNGEGTSKDSKKGAVQCPTCHKTFLSKYYLKVHNRRHTGEKPFKCGKCGKCYFRKENLLEHEARNCLTRTELVFSCSKCSMTFKKRQELRHHTVMHTGVMPNKCTSCPEQFMQKRDLKIHMIKVHGAPKPHACPLCPKCFLSRTELRLHEASKHRGEKLFVCEECGHRASSRNGLQMHIKAIHRNERPFVCQLCNHAFTQKANLSMHLRTHTGEKPFQCHLCGKTFRTQASLDKHHRTHTGERPFSCEFCEQRFTEKGPLLRHIASKHQEGRPHFCQICNKTFKAIEQLRVHVRRHKGMRKFECTLCGYKFTRQAHLRRHTQIHNRMENYSPRQRRLRNLVVEDASAAAASSGLPVQTEAQAEPADIVSIVIQQEGAAETGGEQASYPVTDGAVNAEQTGFALAEREDGVAQTEFTVADVMEQTLLVRVQEAYPIHQSDVVVEIPNTEADRKD.
For Research Use Only | Not For Clinical Use.
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