Mouse Anti-Zebrafish ache Antibody (CBMOAB-64630FYA)


Cat: CBMOAB-64630FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityZebrafish (Danio rerio)
CloneMO64630FYA
SpecificityThis antibody binds to Zebrafish ache.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Other locations; Extracellular region or secreted

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionAcetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.
Product OverviewMouse Anti-Zebrafish ache Antibody is a mouse antibody against ache. It can be used for ache detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAcetylcholinesterase; AChE; EC 3.1.1.7; ach
UniProt IDQ9DDE3
Protein RefseqThe length of the protein is 634 amino acids long.
The sequence is show below: MKTSDILLLPTVLLTFLFHNCFAQAEPDLVVATRLGRVQGTRLPVPDRSHVIAFLGIPYAEPPIGKRRFKRAEPKKPWNNVFEAKEFSNACYQFVDTSYPGFPGIEMWNPNRVMSEDCLYLNVWVPPTPRPQNLTVMVWIYGGGFYSGSSSLDVYDGRYLAYTEKVVVVSMNYRVGAFGFLALNGSSDAPGNVGLYDQRLALQWVQENIHFFGGNPKQVTIFGESAGAASVGMHVLSPDSRPLFTRAILQSGVPNTPWATVTFDEARRRTTKLGKLVGCTWGNDTELIDCLRNKHPQELIDQEWQVLPWSSLFRFSFVPVVDGVFFPDTPDAMISSGNFKYTQILLGVNQDEGSYFLLYGAPGFSKDNESLISREDFLESVKMGVPHANDIGLEAVILQYTDWMDENNGQKNRDAMDDIVGDQNVICPLQHFAKSYAQYAALHAQSSAAAPGTLGWGNSGPTGYNSGNSHGAVYLYLFDHRASNLAWPEWMGVIHGYEIEFVFGLPLEKRLNYTAEEEKLSRRIMRYWANFARTGNPNVNTDGTMDSRRRWPQFSANEQKHVGLNTEPMKVHKGLRTQFCALWNRFLPRLLNITDNIDDVERQWKVEFHRWSSYMMHWKSQFDHYSKQERCTDL.
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For Research Use Only | Not For Clinical Use.
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