AibGenesis™ Mouse Anti-nploc4 Antibody (CBMOAB-89751FYA)
Cat: CBMOAB-89751FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-89751FYA | Monoclonal | Zebrafish (Danio rerio), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset | WB, ELISA | MO89751FYA | 100 µg | ||
| MO-AB-05722H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO05722C | 100 µg | ||
| MO-AB-11854W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO11854W | 100 µg | ||
| MO-AB-60258W | Monoclonal | Marmoset | WB, ELISA | MO60258W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Zebrafish (Danio rerio), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset |
| Clone | MO89751FYA |
| Specificity | This antibody binds to Zebrafish nploc4. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I (PubMed:26471729). (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-Zebrafish nploc4 Antibody is a mouse antibody against nploc4. It can be used for nploc4 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Nploc4 protein; Nuclear protein localization 4 homolog (S. cerevisiae); nploc |
| UniProt ID | Q7ZVI8 |
| Protein Refseq | The length of the protein is 624 amino acids long. The sequence is show below: MAESIIVRIQSPDGMKKISSTKHETAAAFLKKVAKEFGFSSNGFSVYLNRNKTGEILSQNKALSLLKIKHGDMLFLYPSSAGPSSENMDTAQPHTSSSFPSFPSSSSSSSSLSRSHSAPQIPEDDIDQYLSKQEGKIYRNRDPQLCRHGAMGKCVHCVPLEPFDEDYLNHLDPPVKHMSFHAYIRKLTGGADKGKFVALENISCKIKSGCEGHPPWPEGICTKCQPSAITLNRQKYRHVDNIMFENHTIADRFLDFWRKTGNQRMGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIATQNSLELIEDPKADAVEEIAAKLGLRKVGWIFTDLLSEDTRIGTVRYTRNKDSYFLSAEECITAGHFQNQQANMCRLSPDGHFGSKFVTVVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCRDAPELGYAKESSTEQYVPDVFYKDKDKFGNDITHLARPLPVEYLIIDITTTFPKDPVFTFSSTFRFPIENRDALGETQDFHSLATYLSQCTSSTSFLDIVSDFHLLLFLVTNEVMPLQDSIGLLLDAVKTSNEELAQTWKKSEQWATIEQLCSTVGGQSSGSLDYAMGGPPLPQSSSAVWSCLHCTFMNQPGTEHCEMCSLPRS. |
For Research Use Only | Not For Clinical Use.
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