Mouse Anti-Zebrafish pdp1 Antibody (CBMOAB-64036FYA)
Cat: CBMOAB-64036FYA
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Zebrafish (Danio rerio) |
| Clone | MO64036FYA |
| Specificity | This antibody binds to Zebrafish pdp1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Mitochondrion |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
| Product Overview | Mouse Anti-Zebrafish pdp1 Antibody is a mouse antibody against pdp1. It can be used for pdp1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Zgc:174908 protein; pdp1 |
| UniProt ID | A9JRU2 |
| Protein Refseq | The length of the protein is 519 amino acids long. The sequence is show below: MAATSQVFRVIHGRRFGQIFVPAITCQICIQTPHPCSSAAQTHISDQRWRFQSRGYRTSPARHTYYLTPPQVNSILKANEYNFKVPEFDGKNLSSVMGFDSNQLPANAPIEDRRSAATCLQTRGMLYGVFDGHAGCACAQALSERLFYYIAVSLLPHETLIELENAVENGRPLHPILQWHKHPNDYFSKEASRLYFSSLRTYWQELLDLSVPGEQPEVAEALVTAFKRLDNDISLEAQVGDPNAFLHYWVLRVAFSGATACVAHIDGNELHVANTGDGRAVLGVQEPDGSFSALTLTNDHNAQNESEVQRVRSEHPHSEAKTVVKQDRLLGLLMPFRAFGDVKFKWSIELQRRVLESGPDQLHENEHAKFIPPNYHTPPYLTAEPEVTRHRLRPQDRFLVLGSDGLWETLHRQEVVRIVGEHLTGVHQQLPVSVGGFKVTLGQMQGLLQERKARISSTFEDQNAATHLIRHAVGSNEFGMVDHERLSKMLSLPEELARMYRDDITIIIVQFNPHVIGGQ. |
See other products for " pdp1 "
| MO-AB-06155H | Mouse Anti-Frog pdp1 Antibody (MO-AB-06155H) |
| MO-AB-61255W | Mouse Anti-Marmoset PDP1 Antibody (MO-AB-61255W) |
| CBMOAB-08279HCB | Mouse Anti-C. elegans PDP1 Antibody (CBMOAB-08279HCB) |
| MO-AB-17728R | Mouse Anti-Cattle PDP1 Antibody (MO-AB-17728R) |
| CBMOAB-27410FYA | Mouse Anti-D. melanogaster Pdp1 Antibody (CBMOAB-27410FYA) |
For Research Use Only | Not For Clinical Use.
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