Mouse Anti-PDP1 Antibody (MO-AB-61255W)


Cat: MO-AB-61255W
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Lot Number

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  • Specifications
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MO-AB-61255W Monoclonal Marmoset, C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Fruit fly (Drosophila melanogaster) WB, ELISA MO61255W 100 µg
CBMOAB-27410FYA Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO27410FYA 100 µg
CBMOAB-08279HCB Monoclonal C. elegans (Caenorhabditis elegans) WB, ELISA MO08279HB 100 µg
MO-AB-17728R Monoclonal Cattle (Bos taurus) WB, ELISA MO17728R 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityMarmoset, C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Fruit fly (Drosophila melanogaster)
CloneMO61255W
SpecificityThis antibody binds to Marmoset PDP1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionPyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Product OverviewMouse Anti-Marmoset PDP1 Antibody is a mouse antibody against PDP1. It can be used for PDP1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesPyruvate dehyrogenase phosphatase catalytic subunit 1 isoform 2; PDP1
UniProt IDF7E6B2
Protein RefseqThe length of the protein is 562 amino acids long.
The sequence is show below: MCVCPGPRRIGIPVRSSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSSPYISQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE.
See other products for " pdp1 "
For Research Use Only | Not For Clinical Use.
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