MGC82628 protein
Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Mouse Anti-pdp1 Antibody (CBMOAB-64036FYA) (CAT#: CBMOAB-64036FYA)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Fruit fly (Drosophila melanogaster)
- Application: WB, ELISA
- Protein: Submitted name: Pyruvate dehyrogenase phosphatase catalytic subunit 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Zgc:174908 protein, pdp1
Mouse Anti-pdp1 Antibody (MO-AB-06155H) (CAT#: MO-AB-06155H)
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- Host species: Mouse
- Species Reactivity: Frog (Xenopus laevis), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Fruit fly (Drosophila melanogaster)
- Application: WB, ELISA
- Protein: Submitted name: MGC82628 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: MGC82628 protein, pdp1, MGC82628
Mouse Anti-PDP1 Antibody (MO-AB-61255W) (CAT#: MO-AB-61255W)
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- Host species: Mouse
- Species Reactivity: Marmoset, C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Fruit fly (Drosophila melanogaster)
- Application: WB, ELISA
- Protein: Submitted name: Pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform 2, PDP1
