Mouse Anti-E. coli sulA Antibody (CBMOAB-2674YC)


Cat: CBMOAB-2674YC
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityE. coli (Escherichia coli )
CloneMO2674YC
SpecificityThis antibody binds to Escherichia coli K-12 sulA.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionComponent of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. The effect of overexpression of SulA is neutralized by antitoxin CbeA (yeeU) (PubMed:22515815). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-E. coli sulA Antibody is a mouse antibody against sulA. It can be used for sulA detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesCell division inhibitor SulA; sulA; sfiA; b0958 JW0941
UniProt IDP0AFZ5
Protein RefseqThe length of the protein is 169 amino acids long. The sequence is show below: MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH.
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For Research Use Only | Not For Clinical Use.
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