Alpha-2-Macroglobulin

The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]

  • Mouse Anti-Rhesus A2M Antibody (CBMOAB-34738FYA) (CAT#: CBMOAB-34738FYA)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Submitted name: Alpha-2-macroglobulin
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Alpha-2-macroglobulin, A2M
  • Mouse Anti-Cattle A2M Antibody (MO-AB-06722R) (CAT#: MO-AB-06722R)

    • Host species: Mouse
    • Species Reactivity: Cattle (Bos taurus)
    • Application: WB, ELISA
    • Protein: Alpha-2-macroglobulin
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Alpha-2-macroglobulin, Alpha-2-M, A2M
  • Mouse Anti-Chimpanzee A2M Antibody (MO-AB-17838W) (CAT#: MO-AB-17838W)

    • Host species: Mouse
    • Species Reactivity: Chimpanzee (Pan troglodytes)
    • Application: WB, ELISA
    • Protein: Submitted name: Alpha-2-macroglobulin
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Alpha-2-macroglobulin, A2M
  • Mouse Anti-Pig A2M Antibody (MO-AB-23433R) (CAT#: MO-AB-23433R)

    • Host species: Mouse
    • Species Reactivity: Pig (Sus scrofa)
    • Application: WB, ELISA
    • Protein: Submitted name: Alpha-2-macroglobulin
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Alpha-2-macroglobulin, A2M
  • Mouse Anti-Marmoset A2M Antibody (MO-AB-50149W) (CAT#: MO-AB-50149W)

    • Host species: Mouse
    • Species Reactivity: Marmoset
    • Application: WB, ELISA
    • Protein: Submitted name: Uncharacterized protein
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Alpha-2-macroglobulin, A2M
  • Mouse Anti-Frog a2m Antibody (MO-AB-01108H) (CAT#: MO-AB-01108H)

    • Host species: Mouse
    • Species Reactivity: Frog (Xenopus laevis)
    • Application: WB, ELISA
    • Protein: Submitted name: LOC100158443 protein
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: LOC100158443 protein, a2m, LOC100158443
  • Rabbit Anti-a2M Antibody (MOFY-0622-FY197) (CAT#: MOFY-0622-FY197)

    • Host species: Rabbit
    • Species Reactivity: Rabbit
    • Application: WB, IHC, ICC, IP
    • Protein: Alpha-2-Macroglobulin
    • Size: 100µL
    • Conjugate: None
    • Alternative Names: A2MG, A2mg, CPAMD5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
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