Alpha-2-Macroglobulin
The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
Mouse Anti-A2M Antibody (CBMOAB-34738FYA) (CAT#: CBMOAB-34738FYA)
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- Host species: Mouse
- Species Reactivity: Rhesus (Macaca mulatta), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Pig (Sus scrofa), Rabbit
- Application: WB, ELISA
- Protein: Submitted name: Alpha-2-macroglobulin
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Alpha-2-macroglobulin, A2M
Mouse Anti-A2M Antibody (MO-AB-06722R) (CAT#: MO-AB-06722R)
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- Host species: Mouse
- Species Reactivity: Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Pig (Sus scrofa), Rabbit
- Application: WB, ELISA
- Protein: Alpha-2-macroglobulin
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Alpha-2-macroglobulin, Alpha-2-M, A2M
For Research Use Only | Not For Clinical Use.
