ATP-binding cassette sub-family D member 2, Fragment

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.

  • Mouse Anti-ABCD2 Antibody (CBMOAB-34839FYA) (CAT#: CBMOAB-34839FYA)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta), Cattle (Bos taurus), Zebrafish (Danio rerio)
    • Application: WB, ELISA
    • Protein: Submitted name: ATP binding cassette subfamily D member 2
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: ABCD2
  • Mouse Anti-ABCD2 Antibody (MO-AB-23448R) (CAT#: MO-AB-23448R)

    • Host species: Mouse
    • Species Reactivity: Pig (Sus scrofa), Cattle (Bos taurus), Zebrafish (Danio rerio)
    • Application: WB, ELISA
    • Protein: Submitted name: ATP-binding cassette sub-family D member 2
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: ATP-binding cassette sub-family D member 2, Fragment, ABCD2
  • Mouse Anti-ABCD2 Antibody (MO-AB-50206W) (CAT#: MO-AB-50206W)

    • Host species: Mouse
    • Species Reactivity: Marmoset, Cattle (Bos taurus), Zebrafish (Danio rerio)
    • Application: WB, ELISA
    • Protein: Submitted name: ATP binding cassette subfamily D member 2
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: ATP-binding cassette sub-family D member 2, ABCD2
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