Aminoacylase-1

This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.

  • Mouse Anti-D. melanogaster Acy1 Antibody (CBMOAB-00919FYA) (CAT#: CBMOAB-00919FYA)

    • Host species: Mouse
    • Species Reactivity: Fruit fly (Drosophila melanogaster)
    • Application: WB, ELISA
    • Protein: Submitted name: RE32110p
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Aminoacylase-1, EC 3.5.1.14, N-acyl-L-amino-acid amidohydrolase
  • Mouse Anti-C. elegans ACY1 Antibody (CBMOAB-00367HCB) (CAT#: CBMOAB-00367HCB)

    • Host species: Mouse
    • Species Reactivity: C. elegans (Caenorhabditis elegans)
    • Application: WB, ELISA
    • Protein: Submitted name: Adenylyl CYclase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Adenylyl CYclase, acy-1
  • Mouse Anti-Zebrafish acy1 Antibody (CBMOAB-64840FYA) (CAT#: CBMOAB-64840FYA)

    • Host species: Mouse
    • Species Reactivity: Zebrafish (Danio rerio)
    • Application: WB, ELISA
    • Protein: N-acyl-L-amino-acid amidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Aminoacylase-1, EC 3.5.1.14, N-acyl-L-amino-acid amidohydrolase, acy1, zgc:5560
  • Mouse Anti-Cattle ACY1 Antibody (MO-AB-06978R) (CAT#: MO-AB-06978R)

    • Host species: Mouse
    • Species Reactivity: Cattle (Bos taurus)
    • Application: WB, ELISA
    • Protein: N-acyl-L-amino-acid amidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Aminoacylase-1, EC 3.5.1.14, N-acyl-L-amino-acid amidohydrolase, ACY1, ABHD14A
  • Mouse Anti-Chimpanzee ACY1 Antibody (MO-AB-25680W) (CAT#: MO-AB-25680W)

    • Host species: Mouse
    • Species Reactivity: Chimpanzee (Pan troglodytes)
    • Application: WB, ELISA
    • Protein: N-acyl-L-amino-acid amidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Aminoacylase-1, EC 3.5.1.14, N-acyl-L-amino-acid amidohydrolase, ACY1
  • Mouse Anti-Dog ACY1 Antibody (MO-AB-28810W) (CAT#: MO-AB-28810W)

    • Host species: Mouse
    • Species Reactivity: Dog (Canis lupus familiaris)
    • Application: WB, ELISA
    • Protein: N-acyl-L-amino-acid amidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Aminoacylase-1, EC 3.5.1.14, N-acyl-L-amino-acid amidohydrolase, ACY1
  • Mouse Anti-Nile tilapia acy1 Antibody (MO-AB-32805H) (CAT#: MO-AB-32805H)

    • Host species: Mouse
    • Species Reactivity: Nile tilapia (Oreochromis niloticus)
    • Application: WB, ELISA
    • Protein: N-acyl-L-amino-acid amidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Aminoacylase-1, EC 3.5.1.14, N-acyl-L-amino-acid amidohydrolase, LOC100694810
  • Mouse Anti-Horse ACY1 Antibody (MO-AB-43579W) (CAT#: MO-AB-43579W)

    • Host species: Mouse
    • Species Reactivity: Horse (Equus caballus)
    • Application: WB, ELISA
    • Protein: N-acyl-L-amino-acid amidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Aminoacylase-1, EC 3.5.1.14, N-acyl-L-amino-acid amidohydrolase, ACY1
  • Mouse Anti-Marmoset ACY1 Antibody (MO-AB-50413W) (CAT#: MO-AB-50413W)

    • Host species: Mouse
    • Species Reactivity: Marmoset
    • Application: WB, ELISA
    • Protein: N-acyl-L-amino-acid amidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Aminoacylase-1, EC 3.5.1.14, N-acyl-L-amino-acid amidohydrolase, ABHD14A-ACY1
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