Protein kinase Bub1

This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.

  • Mouse Anti-BUB1 Antibody (CBMOAB-00550CR) (CAT#: CBMOAB-00550CR)

    • Host species: Mouse
    • Species Reactivity: Yeast, A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Rhesus (Macaca mulatta), Zebrafish (Danio rerio)
    • Application: WB, ELISA
    • Protein: Checkpoint serine/threonine-protein kinase BUB1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Checkpoint serine/threonine-protein kinase BUB1, EC 2.7.11.1, BUB1, YGR188C
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