Cbl proto-oncogene, E3 ubiquitin protein ligase B
This gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell receptor, and high affinity immunoglobulin epsilon receptor activation. Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and infections. E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
Mouse Anti-Rhesus CBLB Antibody (CBMOAB-38227FYA) (CAT#: CBMOAB-38227FYA)
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- Host species: Mouse
- Species Reactivity: Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Protein: E3 ubiquitin-protein ligase CBL
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: E3 ubiquitin-protein ligase CBL-B, CBLB
Mouse Anti-Chimpanzee CBLB Antibody (MO-AB-12895W) (CAT#: MO-AB-12895W)
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- Host species: Mouse
- Species Reactivity: Chimpanzee (Pan troglodytes)
- Application: WB, ELISA
- Protein: E3 ubiquitin-protein ligase CBL
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Cas-Br-M (Murine) ecotropic retroviral transforming sequence b, CBLB
Mouse Anti-Pig CBLB Antibody (MO-AB-24352R) (CAT#: MO-AB-24352R)
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- Host species: Mouse
- Species Reactivity: Pig (Sus scrofa)
- Application: WB, ELISA
- Protein: E3 ubiquitin-protein ligase CBL
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Cbl proto-oncogene, E3 ubiquitin protein ligase B, CBLB
Mouse Anti-Marmoset CBLB Antibody (MO-AB-52307W) (CAT#: MO-AB-52307W)
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- Host species: Mouse
- Species Reactivity: Marmoset
- Application: WB, ELISA
- Protein: E3 ubiquitin-protein ligase CBL
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: E3 ubiquitin-protein ligase CBL-B, CBLB
Mouse Anti-Zebrafish cblb Antibody (CBMOAB-69165FYA) (CAT#: CBMOAB-69165FYA)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: E3 ubiquitin-protein ligase CBL
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: cblb, Cbl Proto-Oncogene B
