Mouse Anti-Zebrafish cblb Antibody (CBMOAB-69165FYA)


Cat: CBMOAB-69165FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityZebrafish (Danio rerio)
CloneMO69165FYA
SpecificityThis antibody binds to Zebrafish cblb.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell receptor, and high affinity immunoglobulin epsilon receptor activation. Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and infections.
Product OverviewMouse Anti-Zebrafish cblb Antibody is a mouse antibody against cblb. It can be used for cblb detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Namescblb; Cbl Proto-Oncogene B
UniProt IDF1Q5B6
Protein RefseqThe length of the protein is 939 amino acids long.
The sequence is show below: MATALSGRPPNNRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQNPRLQLKNSPPYILDILPDTYQHLRLILCKYEENQRLTQLSENDYFKVYIDSLMKKSKRAIRLFKEAKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPGGQFQGDTFRITKADAAEFWRRSFGEKTIVPWKMFRQCLHDVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYINKPGSYIFRLSCTRLGQWAIGYVTSDGNILQTIPHNKPLFQALIDGCREGFYLFPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQDSDGQGCPFCRCEIKGTEPIIVDPFDPRNEGAKCFHLDHFSSPLLDPDDDDDRDGLLVIDHIKKSMEIQNSPIMSPNSSPVCERRKTAADHMGPHLNIPPVPPRLDLIRSPAPSPTASPKSSPGMSRKQDKPLPAPPPPQRDPPPPPPPERPPHLPQEGRAAWLVTPSSGLPRDPRAPLEAWSPKDSTALSDCRTSAADRSPKLAHAAPAHINERPLSCSSADLGLNRNRLIAQTECSKSFVNGLLPGDEYDIPPLRHSPPILDNNQRHMNPFTSPRSLTDRVEDDYQIPSSHPVCITQPAICIPFRIPNRALENGSTDHSTDIKKHKPPEHGGFDSGPLISAVSHTTQCPLHNRTPSDYDILLPPQASPMEDPFNALPPSQPPPPPPIRNSFTEASSSSLYPRPARPSSGHDHFLLSPDTFIDSLNNSAPSPPVRRQTGDNMKTPFRAPQDYDQLPPTSVAGDCFRAPERPPKPLPRIIPPDIHRRPHESSRENVDAKIAKLMGEGYSFEDVKRALMIAQNKVDVARNILREFALVAPRQGL.
For Research Use Only | Not For Clinical Use.
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