Cartilage intermediate layer protein 1
Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.
Mouse Anti-CILP Antibody (CBMOAB-39279FYA) (CAT#: CBMOAB-39279FYA)
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- Host species: Mouse
- Species Reactivity: Rhesus (Macaca mulatta), Marmoset, Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: Submitted name: Cartilage intermediate layer protein 1 preproprotein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Cartilage intermediate layer protein 1 preproprotein, CILP
Mouse Anti-CILP Antibody (MO-AB-24615R) (CAT#: MO-AB-24615R)
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- Host species: Mouse
- Species Reactivity: Pig (Sus scrofa), Marmoset, Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: Submitted name: Cartilage intermediate layer protein 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Cartilage intermediate layer protein 1, CILP
For Research Use Only | Not For Clinical Use.
