Periplasmic protein CpxP

Acts as an auxiliary protein in the Cpx two-component envelope stress response system, helping modulate the Cpx response systems response to some inducers (PubMed:25207645, PubMed:16303867). Binds the periplasmic domain of sensor histidine kinase CpxA, inhibiting induction of the Cpx envelope stress response in the absence of inducer; overexpression decreases Cpx pathway activity (PubMed:16166523, PubMed:21317318). Some periplasmic stimulii (shown for P pili subunit PapE and probably 0.3 M NaCl) increase CpxP's susceptibility to DegP, leading to CpxP degradation, inducing the Cpx pathway (PubMed:16166523, PubMed:16303867). Aids in combating extracytoplasmic protein-mediated toxicity (PubMed:9473036, PubMed:16303867, PubMed:21239493). Overexpression leads to degradation by DegP of misfolded P pili subunits in the periplasm (tested using PapE) (PubMed:21239493). Inhibits autophosphorylation of CpxA in reconstituted liposomes by 50% but has no effect on phosphatase activity of CpxA (PubMed:17259177, PubMed:21239493). Has mild protein chaperone activity (PubMed:21317898, PubMed:21239493).

  • Mouse Anti-E. coli cpxP Antibody (CBMOAB-0416YC) (CAT#: CBMOAB-0416YC)

    • Host species: Mouse
    • Species Reactivity: E. coli (Escherichia coli )
    • Application: WB, ELISA
    • Protein: Periplasmic protein CpxP
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: Periplasmic protein CpxP, cpxP, yiiO, b4484 JW5558
  • Mouse Anti-E. coli cpxP (QLRDVTQWQKSS) Antibody (CAT#: MOXC-002W)

    • Host species: Mouse
    • Species Reactivity: E. coli
    • Application: WB, ELISA
    • Protein: Periplasmic protein CpxP
    • Size: 0.2mg, 0.5mg, 1mg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, PE, PerCP
    • Alternative Names: Periplasmic protein CpxP, cpxP, yiiO, b4484 JW5558
  • Mouse Anti-E. coli cpxP (EVGSGDNWHPGE) Antibody (CAT#: MOXC-003W)

    • Host species: Mouse
    • Species Reactivity: E. coli
    • Application: WB, ELISA
    • Protein: Periplasmic protein CpxP
    • Size: 0.2mg, 0.5mg, 1mg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, PE, PerCP
    • Alternative Names: Periplasmic protein CpxP, cpxP, yiiO, b4484 JW5558
  • Mouse Anti-E. coli cpxP (QARHEQPPVNVS) Antibody (CAT#: MOXC-004W)

    • Host species: Mouse
    • Species Reactivity: E. coli
    • Application: WB, ELISA
    • Protein: Periplasmic protein CpxP
    • Size: 0.2mg, 0.5mg, 1mg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, PE, PerCP
    • Alternative Names: Periplasmic protein CpxP, cpxP, yiiO, b4484 JW5558
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