Hypoxia Inducible Factor 1 Alpha Subunit
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
Mouse Anti-HIF1A Antibody (MO-AB-02284Y) (CAT#: MO-AB-02284Y)
-
- Host species: Mouse
- Species Reactivity: Chicken (Gallus gallus), Bovine, Human, Mouse, Rat, Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Frog (Xenopus laevis), Goat (Capra hircus), Horse (Equus caballus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Guinea pig (Cavia porcllus), Primate, Frog (Xenopus), Zebrafish (Danio rerio), Marmoset, Pig (Sus scrofa), Sheep (Ovis aries)
- Application: WB, ELISA
- Protein: Hypoxia-inducible factor 1-alpha
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Hypoxia-inducible factor 1-alpha, HIF1A
For Research Use Only | Not For Clinical Use.
