Isocitrate Dehydrogenase [Nadp]

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

  • Mouse Anti-IDH1 Antibody (CBMOAB-35151FYC) (CAT#: CBMOAB-35151FYC)

    • Host species: Mouse
    • Species Reactivity: A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cat (Felis catus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Gorilla, Guinea pig (Cavia porcellus), Horse (Equus caballus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Rhesus (Macaca mulatta), Zebrafish (Danio rerio), Mallard (Anas platyrhynchos), Marmoset, Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), S.cerevisiae, Sheep (Ovis aries), Soybean (Glycine max), Yeast, S. cerevisiae (Saccharomyces cerevisiae), Zebrafish
    • Application: WB, ELISA
    • Protein: Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic

  • Mouse Anti-IDH1 Antibody (MO-AB-00646L) (CAT#: MO-AB-00646L)

    • Host species: Mouse
    • Species Reactivity: Elephant (Loxodonta africana), A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cat (Felis catus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Gorilla, Guinea pig (Cavia porcellus), Horse (Equus caballus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Rhesus (Macaca mulatta), Zebrafish (Danio rerio), Mallard (Anas platyrhynchos), Marmoset, Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), S.cerevisiae, Sheep (Ovis aries), Soybean (Glycine max), Yeast, S. cerevisiae (Saccharomyces cerevisiae), Zebrafish
    • Application: WB, ELISA
    • Protein: Isocitrate dehydrogenase [NADP]
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Isocitrate dehydrogenase [NADP], EC 1.1.1.42, IDH1

  • Mouse Anti-IDH1 Antibody (MO-AB-06561Y) (CAT#: MO-AB-06561Y)

    • Host species: Mouse
    • Species Reactivity: O. anatinus (Ornithorhynchus anatinus), A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cat (Felis catus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Gorilla, Guinea pig (Cavia porcellus), Horse (Equus caballus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Rhesus (Macaca mulatta), Zebrafish (Danio rerio), Mallard (Anas platyrhynchos), Marmoset, Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), S.cerevisiae, Sheep (Ovis aries), Soybean (Glycine max), Yeast, S. cerevisiae (Saccharomyces cerevisiae), Zebrafish
    • Application: WB, ELISA
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Isocitrate dehydrogenase [NADP], EC 1.1.1.42, IDH1

  • Mouse Anti-IDH1 Antibody (MO-AB-13940R) (CAT#: MO-AB-13940R)

    • Host species: Mouse
    • Species Reactivity: Cattle (Bos taurus), A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cat (Felis catus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Gorilla, Guinea pig (Cavia porcellus), Horse (Equus caballus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Rhesus (Macaca mulatta), Zebrafish (Danio rerio), Mallard (Anas platyrhynchos), Marmoset, Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), S.cerevisiae, Sheep (Ovis aries), Soybean (Glycine max), Yeast, S. cerevisiae (Saccharomyces cerevisiae), Zebrafish
    • Application: WB, ELISA
    • Protein: Isocitrate dehydrogenase [NADP] cytoplasmic
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Isocitrate dehydrogenase [NADP] cytoplasmic, IDH, EC 1.1.1.42, Cytosolic NADP-isocitrate dehydrogenase, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, IDH1, ICDH

  • Mouse Anti-IDH1 Antibody (MO-NAB-00176W) (CAT#: MO-NAB-00176W)

    • Host species: Mouse
    • Species Reactivity: Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Cattle (Bos taurus), Rhesus (Macaca mulatta), Sheep (Ovis aries), A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cat (Felis catus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Gorilla, Guinea pig (Cavia porcellus), Horse (Equus caballus), Zebrafish (Danio rerio), Mallard (Anas platyrhynchos), Marmoset, Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), S.cerevisiae, Soybean (Glycine max), Yeast, S. cerevisiae (Saccharomyces cerevisiae), Zebrafish
    • Application: WB, IF, IP, KD, KO
    • Protein: Isocitrate dehydrogenase [NADP] cytoplasmic
    • Size: 100µL
    • Conjugate: unconjugated
    • Alternative Names: Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic
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