Midline-1

The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities.

  • Mouse Anti-D. melanogaster Mid1 Antibody (CBMOAB-23934FYA) (CAT#: CBMOAB-23934FYA)

    • Host species: Mouse
    • Species Reactivity: Fruit fly (Drosophila melanogaster)
    • Application: WB, ELISA
    • Protein: Submitted name: Mid1, isoform A
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: CG33988, RE02133p, Mid1, CG13595
  • Mouse Anti-Yeast MID1 Antibody (CBMOAB-02287CR) (CAT#: CBMOAB-02287CR)

    • Host species: Mouse
    • Species Reactivity: Yeast
    • Application: WB, ELISA
    • Protein: Stretch-activated cation channel MID1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Stretch-activated cation channel MID1, Mating pheromone-induced death protein 2, MID1, YNL291C
  • Mouse Anti-Rhesus MID1 Antibody (CBMOAB-51426FYA) (CAT#: CBMOAB-51426FYA)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: MID1
  • Mouse Anti-Zebrafish mid1 Antibody (CBMOAB-86915FYA) (CAT#: CBMOAB-86915FYA)

    • Host species: Mouse
    • Species Reactivity: Zebrafish (Danio rerio)
    • Application: WB, ELISA
    • Protein: E3 ubiquitin-protein ligase Midline-1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: mid1, Midline 1
  • Mouse Anti-Chicken MID1 Antibody (MO-AB-02907Y) (CAT#: MO-AB-02907Y)

    • Host species: Mouse
    • Species Reactivity: Chicken (Gallus gallus)
    • Application: WB, ELISA
    • Protein: E3 ubiquitin-protein ligase Midline-1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Midline-1, MID1
  • Mouse Anti-Rhesus MID1 Antibody (MO-AB-04413W) (CAT#: MO-AB-04413W)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Submitted name: Midline-1 isoform 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Midline-1 isoform 1, MID1
  • Mouse Anti-Frog mid1 Antibody (MO-AB-05175H) (CAT#: MO-AB-05175H)

    • Host species: Mouse
    • Species Reactivity: Frog (Xenopus laevis)
    • Application: WB, ELISA
    • Protein: E3 ubiquitin-protein ligase Midline-1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Midline 1, mid1, MID1
  • Mouse Anti-Chimpanzee MID1 Antibody (MO-AB-16907W) (CAT#: MO-AB-16907W)

    • Host species: Mouse
    • Species Reactivity: Chimpanzee (Pan troglodytes)
    • Application: WB, ELISA
    • Protein: E3 ubiquitin-protein ligase Midline-1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Midline 1, Opitz / BBB syndrome, MID1
  • Mouse Anti-Marmoset MID1 Antibody (MO-AB-59089W) (CAT#: MO-AB-59089W)

    • Host species: Mouse
    • Species Reactivity: Marmoset
    • Application: WB, ELISA
    • Protein: E3 ubiquitin-protein ligase Midline-1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Midline-1 isoform 1, MID1
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