Mre11
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Mouse Anti-MRE11 Antibody (CBMOAB-00045CR) (CAT#: CBMOAB-00045CR)
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- Host species: Mouse
- Species Reactivity: Yeast, C. elegans (Caenorhabditis elegans), Chimpanzee (Pan troglodytes), Fruit fly (Drosophila melanogaster), Marmoset, Rhesus (Macaca mulatta), Rice (Oryza), Silkworm (Bombyx mori)
- Application: WB, ELISA
- Protein: Double-strand break repair protein MRE11
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Double-strand break repair protein MRE11, MRE11, YMR224C
Mouse Anti-MRE11 Antibody (CBMOAB-36692FYC) (CAT#: CBMOAB-36692FYC)
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- Host species: Mouse
- Species Reactivity: A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Chimpanzee (Pan troglodytes), Fruit fly (Drosophila melanogaster), Marmoset, Rhesus (Macaca mulatta), Rice (Oryza), Silkworm (Bombyx mori)
- Application: WB, ELISA
- Protein: Double-strand break repair protein MRE11
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
- Alternative Names: MRE11 Homolog, Double Strand Break Repair Nuclease, MRE11 Homolog A, Double Strand Break Repair Nuclease, Double-Strand Break Repair Protein MRE11A, Meiotic Recombination 11 Homolog 1, Meiotic Recombination 11 Homolog A, AT-Like Disease, MRE11 Homolog 1, MRE11A, HNGS1, MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae), MRE11 Homolog, Double Strand Break Repair Nuclease A
For Research Use Only | Not For Clinical Use.
