Origin Recognition Complex Subunit 2
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. [provided by RefSeq, Oct 2010]
Mouse Anti-ORC2 Antibody (CBMOAB-37837FYC) (CAT#: CBMOAB-37837FYC)
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- Host species: Mouse
- Species Reactivity: A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Maize (Zea mays), Marmoset, Rhesus (Macaca mulatta), Rice (Oryza), S. cerevisiae, Silkworm (Bombyx mori), Yeast
- Application: WB, ELISA
- Protein: Origin of replication complex subunit 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
- Alternative Names: Origin Recognition Complex Subunit 2, ORC2L, Origin Recognition Complex, Subunit 2 (Yeast Homolog)-Like, Origin Recognition Complex, Subunit 2 Homolog (Yeast), Origin Recognition Complex, Subunit 2-Like (Yeast), Origin Recognition Complex, Subunit 2 Homolog, Origin Recognition Complex Protein 2 Homolog, Origin Recognition Complex, Subunit 2