Severe Acute Respiratory Syndrome Coronavirus 2

Coronavirus disease 2019 is a newly emerging infectious disease that is currently spreading globally. It is caused by a new type of coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The spike (S) protein of SARS-CoV-2 plays a key role in the process of receptor recognition and cell membrane fusion, and is composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain that recognizes and binds to the host receptor angiotensin converting enzyme 2, while the S2 subunit mediates viral cell membrane fusion by forming a six-helix bundle through two heptapeptide repeat domains. In this review, we focused on the latest research progress in the structure, function and development of antiviral drugs targeting S protein.

  • Mouse Anti-SARS-CoV-2 (2019-nCoV) S2 Antibody (CAT#: MO-NAB-00877W)

    • Host species: Mouse
    • Species Reactivity: SARS-CoV-2 (2019-nCoV)
    • Application: WB, ELISA
    • Protein: Spike glycoprotein
    • Conjugate: NONE
    • Alternative Names: S glycoprotein, E2, Peplomer protein, Spike protein S2, S
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