Rabbit Anti-SARS-CoV-2 (2019-nCoV) S2 Antibody (AA 686-1213)


Cat: MO-NAB-00903W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivitySARS-CoV-2 (2019-nCoV)
SpecificityRecognize SARS-CoV-2 S2 protein
ImmunogenRecombinant SARS-CoV-2 S2 protein (Ser686-Pro1213)
EpitopeAA 686-1213
FormatLiquid
BufferPBS, pH7.4, 50% glycerol
StorageStore at 2 to 8°C for one week.
From the date of receipt, store at -20 to -80 °C for 12 months.
Avoid repeated freeze-thaw cycles.

Application Information

ApplicationELISA
Application NotesElisa: 1:4000-1:8000

Target

IntroductionCoronavirus disease 2019 is a newly emerging infectious disease that is currently spreading globally. It is caused by a new type of coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The spike (S) protein of SARS-CoV-2 plays a key role in the process of receptor recognition and cell membrane fusion, and is composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain that recognizes and binds to the host receptor angiotensin converting enzyme 2, while the S2 subunit mediates viral cell membrane fusion by forming a six-helix bundle through two heptapeptide repeat domains. In this review, we focused on the latest research progress in the structure, function and development of antiviral drugs targeting S protein.
Product OverviewProduced in rabbits immunized with purified, Recombinant SARS-CoV-2 S2 Protein
Alternative NamesSpike glycoprotein; E2; Peplomer protein; Spike protein S2; S
UniProt IDP0DTC2
For Research Use Only | Not For Clinical Use.

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