Sequestosome 1
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Mouse Anti-sqstm1 Antibody (CBMOAB-07279FYB) (CAT#: CBMOAB-07279FYB)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Medaka (Oryzias latipes), Rhesus (Macaca mulatta), Sheep (Ovis aries)
- Application: WB, ELISA
- Protein: Submitted name: Sequestosome 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Sequestosome 1, sqstm
For Research Use Only | Not For Clinical Use.
