TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants.
Mouse Anti-D. melanogaster Tab2 Antibody (CBMOAB-32508FYA) (CAT#: CBMOAB-32508FYA)
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- Host species: Mouse
- Species Reactivity: Fruit fly (Drosophila melanogaster)
- Application: WB, ELISA
- Protein: Submitted name: Transcription factor
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Transcription factor, Tab2
Mouse Anti-Zebrafish tab2 Antibody (CBMOAB-08483FYB) (CAT#: CBMOAB-08483FYB)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: TGF-beta-activated kinase 1 and MAP3K7-binding protein 2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, TGF-beta-activated kinase 1-binding protein 2, tab2, map3k7ip
Mouse Anti-Chimpanzee TAB2 Antibody (MO-AB-13178W) (CAT#: MO-AB-13178W)
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- Host species: Mouse
- Species Reactivity: Chimpanzee (Pan troglodytes)
- Application: WB, ELISA
- Protein: Submitted name: TGF-beta activated kinase 1 (MAP3K7) binding protein 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: TGF-beta activated kinase 1 / MAP3K7 binding protein 2, TAB2
Mouse Anti-Maize TAB2 Antibody (MO-AB-49670W) (CAT#: MO-AB-49670W)
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- Host species: Mouse
- Species Reactivity: Maize (Zea mays)
- Application: WB, ELISA
- Protein: Protein TAB2 homolog, chloroplastic
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Tab2 protein, LOC100284484
Mouse Anti-Marmoset TAB2 Antibody (MO-AB-65779W) (CAT#: MO-AB-65779W)
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- Host species: Mouse
- Species Reactivity: Marmoset
- Application: WB, ELISA
- Protein: Submitted name: TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: TGF-beta-activated kinase 1 and MAP3K7-binding protein 2, TAB2
