LOC100037075 protein

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and vitamin D3 receptors. In addition, this subunit interacts with the transcription factor CREB, which has a glutamine-rich activation domain, and binds to other proteins containing glutamine-rich regions. Aberrant binding to this subunit by proteins with expanded polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases.

  • Mouse Anti-Yeast TAF4 Antibody (CBMOAB-04377CR) (CAT#: CBMOAB-04377CR)

    • Host species: Mouse
    • Species Reactivity: Yeast
    • Application: WB, ELISA
    • Protein: Transcription initiation factor TFIID subunit 4
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Transcription initiation factor TFIID subunit 4, MPT-1, TAF suppressor gene 2 protein, TAFII-48, TBP-associated factor 4, TBP-associated factor 48 kDa, TAF4, MPT1 TAF48 TSG2, YMR005W
  • Mouse Anti-C. elegans TAF4 Antibody (CBMOAB-11880HCB) (CAT#: CBMOAB-11880HCB)

    • Host species: Mouse
    • Species Reactivity: C. elegans (Caenorhabditis elegans)
    • Application: WB, ELISA
    • Protein: Submitted name: TAFH domain-containing protein
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Protein TAF-4, taf-4
  • Mouse Anti-Arabidopsis TAF4 Antibody (CBMOAB-44784FYC) (CAT#: CBMOAB-44784FYC)

    • Host species: Mouse
    • Species Reactivity: A. thaliana (Arabidopsis thaliana)
    • Application: WB, ELISA
    • Protein: Transcription initiation factor TFIID subunit 4
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: TATA-Box Binding Protein Associated Factor 4, TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa, TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase II, C1, 130kD, Transcription Initiation Factor TFIID 130 KDa Subunit, Transcription Initiation Factor TFIID 135 KDa Subunit, RNA Polymerase II TBP-Associated Factor Subunit C, TBP-Associated Factor 4, TAF(II)130, TAF(II)135, TAFII-130
  • Mouse Anti-Rhesus TAF4 Antibody (CBMOAB-59682FYA) (CAT#: CBMOAB-59682FYA)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Submitted name: Transcription initiation factor TFIID subunit 4
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Transcription initiation factor TFIID subunit 4, TAF4
  • Mouse Anti-D. melanogaster Taf4 Antibody (CBMOAB-32540FYA) (CAT#: CBMOAB-32540FYA)

    • Host species: Mouse
    • Species Reactivity: Fruit fly (Drosophila melanogaster)
    • Application: WB, ELISA
    • Protein: Submitted name: TBP-associated factor 4, isoform E
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: TBP-associated factor 4, isoform E, Taf4
  • Mouse Anti-Frog taf4 Antibody (MO-AB-08245H) (CAT#: MO-AB-08245H)

    • Host species: Mouse
    • Species Reactivity: Frog (Xenopus laevis)
    • Application: WB, ELISA
    • Protein: Submitted name: LOC100037075 protein
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: LOC100037075 protein, taf4, LOC100037075
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