TNF Gene(Protein Coding) Tumor Necrosis Factor
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
Rat Anti-TNF (AA 77-233, clone NW0127) Antibody (MO-NAB-00208W) (CAT#: MO-NAB-00208W)
-
- Host species: Rat
- Species Reactivity: Rhesus (Macaca mulatta), Cat (Felis catus), Cattle (Bos taurus), Dog (Canis lupus familiaris), Human (Homo sapiens), Mouse (Mus musculus), Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio), Frog (Xenopus laevis), Goat (Capra hircus), Guinea pig (Cavia porcellus), Horse (Equus caballus), O. anatinus (Ornithorhynchus anatinus), O. mykiss (Oncorhynchus mykiss)
- Application: ELISA(Cap)
- Size: 500µg
- Conjugate: unconjugated
- Alternative Names: Tumor Necrosis Factor, Tumor Necrosis Factor Ligand Superfamily Member 2, Cachectin, TNF-Alpha, TNFSF2, TNF-A, TNFA, Tumor Necrosis Factor (TNF Superfamily, Member 2), Tumor Necrosis Factor Ligand 1F
For Research Use Only | Not For Clinical Use.
