Uromodulin

The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]

  • Mouse Anti-Rhesus UMOD Antibody (CBMOAB-61841FYA) (CAT#: CBMOAB-61841FYA)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Uromodulin
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: UMOD
  • Mouse Anti-Cattle UMOD Antibody (MO-AB-22598R) (CAT#: MO-AB-22598R)

    • Host species: Mouse
    • Species Reactivity: Cattle (Bos taurus)
    • Application: WB, ELISA
    • Protein: Uromodulin
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Uromodulin, Tamm-Horsfall urinary glycoprotein, THP, [Cleaved into: Uromodulin, secreted form], UMOD
  • Mouse Anti-Dog UMOD Antibody (MO-AB-33932W) (CAT#: MO-AB-33932W)

    • Host species: Mouse
    • Species Reactivity: Dog (Canis lupus familiaris)
    • Application: WB, ELISA
    • Protein: Uromodulin
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Uromodulin, UMOD
  • Rabbit Anti-UMOD Antibody (MOFY-0722-FY208) (CAT#: MOFY-0722-FY208)

    • Host species: Rabbit
    • Species Reactivity: Dog, Human, Mouse
    • Application: WB, IHC, ICC, IP
    • Protein: Uromodulin
    • Size: 100µL
    • Conjugate: None
    • Alternative Names: Uromodulin, Tamm-Horsfall Urinary Glycoprotein, Uromucoid, THP, Uromodulin (Uromucoid, Tamm-Horsfall Glycoprotein), Tamm-Horsfall Glycoprotein, ADMCKD2
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