Mouse Anti-A1CF Antibody (CBMOAB-34733FYA)
Cat: CBMOAB-34733FYA
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
CBMOAB-34733FYA | Monoclonal | Rhesus (Macaca mulatta), Frog (Xenopus laevis), Zebrafish (Danio rerio) | WB, ELISA | MO34733FYA | 100 µg | ||
CBMOAB-64266FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO64266FYA | 100 µg | ||
MO-AB-01107H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO01107C | 100 µg |
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rhesus (Macaca mulatta), Frog (Xenopus laevis), Zebrafish (Danio rerio) |
Clone | MO34733FYA |
Specificity | This antibody binds to Rhesus A1CF. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.A1CF (APOBEC1 Complementation Factor) is a Protein Coding gene. Among its related pathways are Gene Expression and Formation of the Editosome. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is RBM47.Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay. |
Product Overview | Mouse Anti-Rhesus A1CF Antibody is a mouse antibody against A1CF. It can be used for A1CF detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | A1CF |
UniProt ID | F7EC11 |
Protein Refseq | The length of the protein is 567 amino acids long. The sequence is show below: MLCSPSLCKLCWKRNKENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKLEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHPIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQAYAAIPSLHFPATKGHLSNRAIIRAPSIRGAAGVRGLGGRGYLAYTGLGRGYQAKGDKREDKLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPFTPPKLSAYVDEAKTYAAEYTLQTLGIPTDGGDAGTMATAATAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGAF. |
For Research Use Only | Not For Clinical Use.
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