AibGenesis™ Mouse Anti-abat Antibody (CBMOAB-64321FYA)


Cat: CBMOAB-64321FYA

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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-64321FYA Monoclonal Zebrafish (Danio rerio), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Goat (Capra hircus), Marmoset WB, ELISA MO64321FYA 100 µg
MO-AB-01124H Monoclonal Frog (Xenopus laevis) WB, ELISA MO01124C 100 µg
MO-AB-06747R Monoclonal Cattle (Bos taurus) WB, ELISA MO06747R 100 µg
MO-AB-13696W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO13696W 100 µg
MO-AB-36650W Monoclonal Goat (Capra hircus) WB, ELISA MO36650W 100 µg
MO-AB-50176W Monoclonal Marmoset WB, ELISA MO50176W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityZebrafish (Danio rerio), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Goat (Capra hircus), Marmoset
CloneMO64321FYA
SpecificityThis antibody binds to Zebrafish abat.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationMitochondrion

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. (From NCBI)
Product OverviewMouse Anti-Zebrafish abat Antibody is a mouse antibody against abat. It can be used for abat detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Namesabat; 4-Aminobutyrate Aminotransferase
UniProt IDI3IRW7
Protein RefseqThe length of the protein is 500 amino acids long.
The sequence is show below: MASSLLTRQLALSLQQNLRLAAPGSRYVSKTATKTVSEFEYDAPSMKTTVPGPKSKELLRQLGEIQNTGAIHFFCNYEESRGNYLVDVDGNRMLDVYTQISSIPIGYNHPALMKVMTNPNNVSAFVNRPALGILPPENFPEKLAESLLSIAPSGMTKVQTMACGSCSNENAFKSMFIWYRNKERGYATPSEEEVGTCMVNQSPGCPDLSILSFMGAFHGRTLGCLATTHSKAIHKLDIPSFDWPIAPFPKLRYPLEEFERENAQEEARCLEEVEDLIVKWRQKGKPVAGIVIEPIQAEGGDNHASPDFFIKLRNIARKHGCGFHVDEVQTGGGATGKFWAHEHWGLDDPADLVSFSKKMLTGGYFHRDELQPDKPYRIFNTWMGDPSKNLFLSEVLNVIRRENLLEQVTRSGKALLQGLYALQSQYPHLLSGARGQGTFCAINASSDATRDSIMLKARNKGVFLGSCGEKSIRFRPALVFKEYHVHQLLNILNDVLAEHK.
For Research Use Only | Not For Clinical Use.
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