AibGenesis™ Mouse Anti-ACD11 Antibody (CBMOAB-1475FYC)


Cat: CBMOAB-1475FYC

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Lot Number

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  • Specifications
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-1475FYC Monoclonal A. thaliana (Arabidopsis thaliana) WB, ELISA MO1475FC 100 µg
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CBMOAB-61501FYC Monoclonal A. thaliana (Arabidopsis thaliana) WB, ELISA MO61501FYC 100 µg
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
CloneMO1475FC
SpecificityThis antibody binds to Arabidopsis ACD11.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationCytosol; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionExhibits selective intermembrane transfer of ceramide-1-phosphate (C1P) and phytoceramide-1-phosphate (PubMed:24412362, PubMed:28011644). Does not transport ceramide (Cer) or GalCer, suggesting a requirement for phosphate in the headgroup for functionality (PubMed:24412362). Transports in vitro sphingosine, but not glycosphigolipids (PubMed:11850411). Has also some in vitro activity with sphingomyelin, a lipid not detected in plant tissues (PubMed:18657186). The transport function may be not directly involved in regulating cell death. Rather, perturbations in the function of ACD11 or related components could be monitored by R-proteins, which then mediate defense and programmed cell death (PCD), as proposed in the guard hypothesis (Probable). C1P transfer is stimulated by phosphatidylserine in C1P source vesicles (PubMed:28011644). Regulates autophagy, inflammasome mediated IL1B and IL18 processing, and pyroptosis, but not apoptosis (PubMed:28011644). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-Arabidopsis ACD11 Antibody is a mouse antibody against ACD11. It can be used for ACD11 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAt2g34690; Glycolipid transfer protein; Putative uncharacterized protein At2g34690; ACD11; At2g34690
UniProt IDO64587
Protein RefseqThe length of the protein is 206 amino acids long. The sequence is show below: MADSEADKPLRKISAAFKKLAIIVNSPNPEVPVTQFSHACSLVSPLFGCLGIAFKFAEMDYVAKVDDLVRASSSISTLVVMMDKDIEADCVRKAGSHTRNLLRVKRGLDMVKVLFEQIIASEGDNSLKDPATKSYAQVFAPHHGWAIRKAVSLGMYALPTRAHLLNMLKEDEAAAKIHMQSYVNSSAPLITYLDNLFLSKQLGIDW.
For Research Use Only | Not For Clinical Use.
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