Mouse Anti-ACO1 Antibody (CBMOAB-00292HCB)


Cat: CBMOAB-00292HCB
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-00292HCB Monoclonal WB, ELISA MO00292HB 100 µg
CBMOAB-1532FYC Monoclonal A. thaliana (Arabidopsis thaliana) WB, ELISA MO1532FC 100 µg
CBMOAB-34963FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO34963FYA 100 µg
CBMOAB-64658FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO64658FYA 100 µg
CBMOAB-18474FYB Monoclonal Rice (Oryza) WB, ELISA MO18474FYB 100 µg
MO-AB-24270W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO24270W 100 µg
MO-AB-28222W Monoclonal Cucumber (Cucumis sativus) WB, ELISA MO28222W 100 µg
MO-AB-36051W Monoclonal French-bean WB, ELISA MO36051W 100 µg
MO-AB-38810W Monoclonal Grape (Vitis vinifera) WB, ELISA MO38810W 100 µg
MO-AB-50324W Monoclonal Marmoset WB, ELISA MO50324W 100 µg
MO-AB-06893R Monoclonal Cattle (Bos taurus) WB, ELISA MO06893R 100 µg
MO-AB-01175H Monoclonal Frog (Xenopus laevis) WB, ELISA MO01175C 100 µg
MO-AB-34092H Monoclonal Tomato (Lycopersicon esculentum) WB, ELISA MO34092C 100 µg
MO-AB-00025Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO00025Y 100 µg
MO-AB-07059Y Monoclonal Rabbit (Oryctolagus cuniculus) WB, ELISA MO07059Y 100 µg
MO-DKB-0020RA Polyclonal WB 100 µL
MO-DKB-01420W Polyclonal Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), Rabbit (Oryctolagus cuniculus), Rhesus (Macaca mulatta) WB, IF 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans), A. thaliana (Arabidopsis thaliana), A. thaliana (Arabidopsis thaliana); S. lycopersicum (Solanum lycopersicum), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Cucumber (Cucumis sativus), French-bean, Frog (Xenopus laevis), Grape (Vitis vinifera), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), Rabbit (Oryctolagus cuniculus), Rhesus (Macaca mulatta), Marmoset, Rice (Oryza), Tomato (Lycopersicon esculentum), Zebrafish (Danio rerio)
CloneMO00292HB
SpecificityThis antibody binds to C. elegans ACO1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationMitochondrion; Other locations; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alternative splicing results in multiple transcript variants.
Product OverviewMouse Anti-C. elegans ACO1 Antibody is a mouse antibody against ACO1. It can be used for ACO1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesProbable cytoplasmic aconitate hydratase; Aconitase; EC 4.2.1.3; Citrate hydro-lyase; Gex-3-interacting protein 22; aco-1 gei-22
Gene ID181324
UniProt IDQ23500
Protein RefseqThe length of the protein is 887 amino acids long. The sequence is show below: MAFNNLIRNLAIGDNVYKYFDLNGLNDARYNELPISIKYLLEAAVRHCDEFHVLKKDVETILDWKNSQRNQAEIPFKPARVILQDFTGVPAVVDLAAMRDAVQNMGADPAKINPVCPVDLVIDHSVQVDHYGNLEALAKNQSIEFERNRERFNFLKWGSKAFDNLLIVPPGSGIVHQVNLEYLARTVFVGKDGVLYPDSVVGTDSHTTMIDGSGVLGWGVGGIEAEAVMLGQPISMVIPEVIGYELVGTLSDTVTSTDLVLTITKNLRDLGVVGKFVEFFGTGVASLSIADRATIANMCPEYGATIGFFPVDSRTIDYLTQTGRDTDYTQRVEQYLKSVGMFVNFTDDSYRPTYTTTLKLDLGSVVPSVSGPKRPHDRVELASLAQDFSKGLTDKISFKAFGLKPEDATKSVTITNHGRTAELTHGSVVIAAITSCTNTSNPSVMLAAGLVAKKAVELGLNVQPYVKTSLSPGSGVVTKYLEASGLLPYLEKIGFNIAGYGCMTCIGNSGPLDEPVTKAIEENNLVVAGVLSGNRNFEGRIHPHVRANYLASPPLAVLYSIIGNVNVDINGVLAVTPDGKEIRLADIWPTRKEVAKFEEEFVKPQFFREVYANIELGSTEWQQLECPAVKLYPWDDASTYIKKVPFFDGMTSELPSQSDIVNAHVLLNLGDSVTTDHISPAGSISKTSPAARFLAGRGVTPRDFNTYGARRGNDEIMARGTFANIRLVNKLASKVGPITLHVPSGEELDIFDAAQKYKDAGIPAIILAGKEYGCGSSRDWAAKGPFLQGVKAVIAESFERIHRSNLIGMGIIPFQYQAGQNADSLGLTGKEQFSIGVPDDLKPGQLIDVNVSNGSVFQVICRFDTEVELTYYRNGGILQYMIRKLIQ.
For Research Use Only | Not For Clinical Use.
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