Mouse Anti-ADD3 Antibody (CBMOAB-35217FYA)
Cat: CBMOAB-35217FYA
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
CBMOAB-35217FYA | Monoclonal | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Horse (Equus caballus), Marmoset | WB, ELISA | MO35217FYA | 100 µg | ||
MO-AB-00054Y | Monoclonal | Chicken (Gallus gallus) | WB, ELISA | MO00054Y | 100 µg | ||
MO-AB-01245H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO01245C | 100 µg | ||
MO-AB-07027R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO07027R | 100 µg | ||
MO-AB-24615W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO24615W | 100 µg | ||
MO-AB-34335W | Monoclonal | Ferret (Mustela Putorius Furo) | WB, ELISA | MO34335W | 100 µg | ||
MO-AB-43582W | Monoclonal | Horse (Equus caballus) | WB, ELISA | MO43582W | 100 µg | ||
MO-AB-50488W | Monoclonal | Marmoset | WB, ELISA | MO50488W | 100 µg |
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Horse (Equus caballus), Marmoset |
Clone | MO35217FYA |
Specificity | This antibody binds to Rhesus ADD3. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Plasma Membrane; Cytoskeleton; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known. |
Product Overview | Mouse Anti-Rhesus ADD3 Antibody is a mouse antibody against ADD3. It can be used for ADD3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | ADD3 |
UniProt ID | F7HJ88 |
Protein Refseq | The length of the protein is 697 amino acids long. The sequence is show below: MSSDASQGVITTPPPPSIPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALGETIEEAFHYIFNVQLACEIQVRALAGAGGVDNLHILDFQKYKAFTYTIAASELCGVWKDAFFFVFQQRSLSFGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPPTMQFEDDDHGPPAPPNPFSHLTEGELEEYKKTIERKQQGLEDAEQELLSDDASSVSQIQSQTQSPQNVPEKLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLTTSTTIENVEITIKSPEKIEEVLSPEGSPSKSPTKKKKKFRTPSFLKKNKKKEKVEA. |
For Research Use Only | Not For Clinical Use.
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