Mouse Anti-ADD3 Antibody (CBMOAB-35217FYA)


Cat: CBMOAB-35217FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-35217FYA Monoclonal Rhesus (Macaca mulatta), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Horse (Equus caballus), Marmoset WB, ELISA MO35217FYA 100 µg
MO-AB-00054Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO00054Y 100 µg
MO-AB-01245H Monoclonal Frog (Xenopus laevis) WB, ELISA MO01245C 100 µg
MO-AB-07027R Monoclonal Cattle (Bos taurus) WB, ELISA MO07027R 100 µg
MO-AB-24615W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO24615W 100 µg
MO-AB-34335W Monoclonal Ferret (Mustela Putorius Furo) WB, ELISA MO34335W 100 µg
MO-AB-43582W Monoclonal Horse (Equus caballus) WB, ELISA MO43582W 100 µg
MO-AB-50488W Monoclonal Marmoset WB, ELISA MO50488W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Horse (Equus caballus), Marmoset
CloneMO35217FYA
SpecificityThis antibody binds to Rhesus ADD3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Cytoskeleton; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionAdducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known.
Product OverviewMouse Anti-Rhesus ADD3 Antibody is a mouse antibody against ADD3. It can be used for ADD3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesADD3
UniProt IDF7HJ88
Protein RefseqThe length of the protein is 697 amino acids long.
The sequence is show below: MSSDASQGVITTPPPPSIPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALGETIEEAFHYIFNVQLACEIQVRALAGAGGVDNLHILDFQKYKAFTYTIAASELCGVWKDAFFFVFQQRSLSFGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPPTMQFEDDDHGPPAPPNPFSHLTEGELEEYKKTIERKQQGLEDAEQELLSDDASSVSQIQSQTQSPQNVPEKLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLTTSTTIENVEITIKSPEKIEEVLSPEGSPSKSPTKKKKKFRTPSFLKKNKKKEKVEA.
For Research Use Only | Not For Clinical Use.
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