Rabbit Anti-AGO1 Antibody (MO-DKB-02393W)
Cat: MO-DKB-02393W
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- Product Details
Specifications
Host species | Rabbit (Oryctolagus cuniculus) |
Species Reactivity | A. thaliana (Arabidopsis thaliana) |
Immunogen | AGO1 synthetic peptide derived from Arabidopsis AT1G48410. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | Peptide affinity purified |
Application Information
Application | WB |
Application Notes | Western Blot (1:1000-1:2000) Note: Optimal dilutions/concentrations should be determined by the end user. |
Target
Introduction | This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. |
Product Overview | This product is a Rabbit antibody against the AGO1. It can be used for AGO1 detection in Western Blot. |
Alternative Names | Argonaute 1, RISC Catalytic Component; Argonaute RISC Catalytic Component 1; Eukaryotic Translation Initiation Factor 2C, 1; Putative RNA-Binding Protein Q99; Argonaute1; EIF-2C 1; EIF2C 1; EIF2C1; HAgo1; AGO1, ATAGO1, ICU9 |
UniProt ID | B2CSW6 |
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For Research Use Only | Not For Clinical Use.
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