Rabbit Anti-AGO1 Antibody (MO-DKB-02393W)


Cat: MO-DKB-02393W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
ImmunogenAGO1 synthetic peptide derived from Arabidopsis AT1G48410.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityPeptide affinity purified

Application Information

ApplicationWB
Application NotesWestern Blot (1:1000-1:2000) Note: Optimal dilutions/concentrations should be determined by the end user.

Target

IntroductionThis gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.
Product OverviewThis product is a Rabbit antibody against the AGO1. It can be used for AGO1 detection in Western Blot.
Alternative NamesArgonaute 1, RISC Catalytic Component; Argonaute RISC Catalytic Component 1; Eukaryotic Translation Initiation Factor 2C, 1; Putative RNA-Binding Protein Q99; Argonaute1; EIF-2C 1; EIF2C 1; EIF2C1; HAgo1; AGO1, ATAGO1, ICU9
UniProt IDB2CSW6
For Research Use Only | Not For Clinical Use.
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