Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below.
Note: Certificate of Analysis not available for kit components. Lot Number
Protein Refseq: The length of the protein is 992 amino acids long. The sequence is show below: MILNARYLYIPCRQKQQQQQQQPQQQQQHQQKQQSQQQQQQQQQQQRSKEQGSQQQQRPQQQAQQQQPSQQQQQSQKQQHPQQQQQQRPQKQQQQFQQDQRPQQQQQQLQKQQQQQGQSWRPQSHDPSPASGSHSHSSSPSHAAALERVEEDFSKIKIDKQKIHSSALLPVLMRPNAHGTRGRAIKVEVNYIQLLLERLIPTAYHYDVDIQPAASRKWQRLAFSEFTKQMFPNHGFAFDGHKNAYAARRLQADVYEQEVKVRDEGRERRFKVAMKEAAVLDMTCLKTYMNNGSTLDKPMSAIQCLDIVLRTAYENNPRFIKFKKSIYVKPDRPDDIGSNHELWYGLFQSALLGARPFLNIDVSHKAFPTGGPVLRILVDMNRGQVPDRVTDWMSRDLHDFLKGMELSYTGPDGVSKLFKYNSIKSPANQQKFKLENGTEMTIDQYFRSKNKQLRYPSLPVLHVGSLVRNVMLPIELCSIPPGQALNKKHPDQCTQFIIRKSATDTATRKRKIMDLFNQIGYNNAPTIKEFGVSVGNNFETVDGRILDPPELSYRNDRRVKPMRGVWRADNMNFIIPSTEITRRELSWTILNLDGRTRPDAIDEFGRNIYQMSLKQGVQLQQFSMKNNFYEPRDMRFAVKDLDNIFDELKKRKIDLVFVVIPSPGRDGDVYAKVKQKAELCVGLLTQCIKSFTLDKKRGDMSTISNIWLKINAKTNGSNHVLAKNFKPPIARKTVMYVGADVTHPSPEQTNIPSVVGVAASYDLEGFRYNCCYRLQGPKDEMIRDLQNIVIKQLRQFKQTNQSLPELIMYYRDGVSEGQFQEVLTIELRAMQAAAASVQQGYKPNITFIVVQKRHHARFFPTANCPTEGRNNNVQPGTIVDRYITAPNQYQFFLVSHAAVQGVAKPTKYCVLYDDENCNPDQLQALTYYLCHMFTRCNRAVSYPAPTYYAHLAAYRGRVYIKDRPLNMNNLTKEYERMQIRTEIQDGHPMFFV.
Protein Refseq: The length of the protein is 782 amino acids long. The sequence is show below: MVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA.
Protein Refseq: The length of the protein is 873 amino acids long. The sequence is show below: MYPIGAAGATELFQGRPSSGSDVSAPASPPAPQEYVFKPPQRPDFGTMGRTIKLQANFFEMEIPKLEVYHYEIDIKPEKCPRGVNREIVEHMVQHFKTQIFGDRKPVYDGRKNLYTAMPLPIGRDKVELEVTIPGEGKDRSFKVAIKWMSCVSLQALHEALSGRLPNIPFETIQALDVVMRHLPSMRYTPVGRSFFTPSEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTIECTVAQYFKDKYKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQDEISKLMRSANFNTDPYVREFGVMVRDDMTEVNGRVLQAPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTELLLKAFTDQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFKHLKYTYQGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQVKNVQKTTPQTLSNLCLKINVKLGGVNNILLPQGRPLVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQQHRQDIIQDLATMVRELLIQFYKSTRFKPTRIIYYRDGISEGQFNQVLQHELLAIREACIKLEKDYQPGITFVVVQKRHHTRLFCMDRNERVGKSGNIPAGTTVDTKITHPFEFDFYLCSHAGIQGTSRPSHYHVLWDDNHFTSDELQVLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQIHQDTLRTMYFA.
Protein Refseq: The length of the protein is 1034 amino acids long. The sequence is show below: MEHERGGGGRGRGRGRGGGRGGGGGDGRGGGYGGAGGGGVGGRGGRGPPGGGGGRGYEPGGGRGYGGGGGGGGRGYGGGGGGGGYESGGGRGYGGGGRGYESGGGRGPGGGGRGHESGGGGGRGGNVWAQPGRGRGGAPAPAPAPAPAARRIQDEGAARSSGTVERIASTEVVRVQPPAPPVAVSRSGTRVPMRRPDGGGSVSKAKVKLLVNHFIVKYRQASTVFHYDIDIKLDISSPKASDKELSKGDFLTVKDELFKDESFRRLSSAVAYDGKRNLFTCAELPDGLFRVKVRSRTYIVSVEFKKKLPLSQLSELPVPREVLQGLDVIVREASSWRKIIIGQGFYSQGRSVPIGPDVVALKGTQQTLKCTQKGLILCVDYSVMPFRKAGPVLDLVQKSVRYLDYRTTLNKHQLDTLKNELKGQRVTVNHRRTKQKYIVKGLTDKPASQITFVDSESGQTKKLLDYYSQQYGKVIEYQMLPCLDLSKSKDKQNYVPIELCDLLEGQRYPKASLNRNSDKTLKEMALIPASSRKEEILELVNADDGPCRGEIAQQFGISLDVQMMEVTGRTLPPPSLKLGTSSGQPPKFNIDQPNCQWNLTRKRLAEGGVLQCWGVVDFSADSGQYALNGNMFIDKIVRKCCDLGVQMNRNPCIVQLLDMEVLSDPHQLFEELNKAKQAAASKKQKLQLLFCPMSDQHPGYKTLKLICETQLGIQTQCFLSFLANKQQGQDQYMSNLALKINGKIGGSNIQLFGESLPRISGAPYMFIGADVNHPSPGNVESPSIAAVVASVDQGASKYVPRIRAQPHRCEVIQHLGDMCKELIGVFEKRNRVKPQRIIYFRDGVSDGQFDMVLNEELADMEKAIKTKDYSPTITVIVAKKRHHTRLFPKDLNQQQTKNGNVLPGTVVDTGVVDPAAYDFYLCSHNGLIGTSRPTHYYSLLDEHGFASDDLQKLVYNLCFVFARCTKPVSLATPVYYADLAAYRGRLYYEGMMMSQPPPSSAASASSASSSGAGASDFRSFPALHEDLVDNMFFI.
Protein Refseq: The length of the protein is 813 amino acids long. The sequence is show below: MDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLATMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA.
Protein Refseq: The length of the protein is 852 amino acids long. The sequence is show below: MLAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLATMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA.
Protein Refseq: The length of the protein is813 amino acids long. The sequence is show below: MDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLSSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA.
Protein Refseq: The length of the protein is 826 amino acids long. The sequence is show below: MYSGAGPALAPPAPPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA.
Protein Refseq: The length of the protein is 1038 amino acids long. The sequence is show below: MARGKNKGGKKEAPDSTKTPSSESQPSESQPSTSQIPTTEPTTTIEDDLGGLGLGESRKRRPRKKPTEKQESLAQAELSNPKLTQTDNPKAEVPKTEAPKTEALKPEAPIPEACKSEAPKSEESKIETRGSKPEAAADKPQDDDDGLGLGLGGGGRKKTRSRKPKFTAVETDIKYSKAPSSEPAIPGPSQSKPITSTASQPIQYVQNKPEVKAAPAAPVLYKIPDKILSPPSRTVPILTNYLAMKITKPLKIYRYDVTFKPDKPKKFIAQVFKLVKSKEFPKEILAFDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGGSSLNAPTDTIQCIDIVLKQGTLESYVKAGRQYFMRPASPIDLGDGLEMWTGLFQSAIFTSKAFINVDVAHKGFPKNQPMIDAFTRDFRLDPNRPVDRQPGRAAEAFNEFIRGLKVVSKILGTGPSSGQLREHICNGVVDPPSRQTFTLENDKGPPVRMTVYEYFMKEKKYRIKYPDLNCLWVGPKDKNIYLPMELVEVAYGQARNKQLNDRQLSTMVREAATPPDVRKRKIEEVIQKMNYSKNQFFKTYGLEIANEFYQVEAKILEAPTLEVGPRQFTVPKKGVWQANCLLKPEALNSWGFIAIELDPRGCNYEDIVSKLMNTGRQMGMNVTQPKMACFNIRINDLHKSMLHALEKQVNFLVVVVSGRGRDYYHKLKQIAELKVGILTHVFKEDTATRRMNPQTARNILLKVNSKLMGINQALENRSIPQCLKGGAVMIVGADVTHPSPDQSNIPSIAAVTASMDTKCYIYNIELSIQTPKKEMIVQFEDIMVDHFHAFKKSQGILPKKVFVFRDGVSEGQFAEVMKSELTGLHRAYQRVAGLNAKPEVLFILVQKRHHTRFFLPGNNARFNVDPGTVVDRDIVHPRELDFYLVSHQAIKGTARPTRYHAVCNDGRIPENEVEHLAYYLCHLYARCMRAVSYPAPTYYAHLACLRARSLTYGEIFNNNDLEKNPKRLRVLDSMLKQSRMFFV.
Protein Refseq: The length of the protein is 860 amino acids long. The sequence is show below: MYSGAGPALAPPAPPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQ.
Protein Refseq: The length of the protein is 860 amino acids long. The sequence is show below: MYSGAGPVLAPPAPPRPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREVVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA.
Protein Refseq: The length of the protein is 862 amino acids long. The sequence is show below: MYSGAGPVLVPPTTTPPLPMPAYTFKPPPRPDFGTSGRTIKLQANVFEMDIPKIEIYHYDIDIKPEKCPRRVNREIVEHMVQHFKAQIFGDRKPVFDGRKNLYTAMPLPIARDKQVELEVTLPGEGKDRIFKVAIKWMACVSLQALHDALAGRHPNVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCANPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPFVREFGIMVKDDMTDVTGRVLQPPSILYGGRSKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKTFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLSAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQVHQDTLRTMYFA.
Protein Refseq: The length of the protein is 853 amino acids long. The sequence is show below: PVLAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKAQIFGDRKPVFDGRKNLYTAMPLPIGREKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVSVPAALQTRLQXXXKITHPSEFDFYLSSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA.
Protein Refseq: The length of the protein is 873 amino acids long. The sequence is show below: MYSSGAAGAAEMLEPPHSSGSIGSDPPSPPVPEYVFKPPSRPDFGTMGRTIKLQANFFEMEIPKLEVYHYDIDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVYDGRKNLYTAMPLPIGREKVELEVTIPGEGKDRSFKVAIKWVSCVSLQALQEALSGRLPNIPFETIQALDVVMRHLPSMRYTPVGRSFFTPSEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTIECTVAQYFKDKYKLILRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSANFNNDPYVREFGVMVRDEMTEVNGRVLQAPSILYGGRQNKAIATPIQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTELLLKAFTDQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFKHLKYTYQGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQVKNVQKTTPQTLSNLCLKINVKLGGVNNILLPQGRPLVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQQHRQDIIQDLATMVRELLIQFYKSTRFKPTRIIYYRDGISEGQFNQVLQHELLAIREACIKLEKDYQPGITFVVVQKRHHTRLFCMDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNHFTSDELQVLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQIHQDTLRTMYFA.
Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity
> 90% was determined by SDS-PAGE
Purification
Purified with Protein A or G affinity chromatography
Application Information
Application
WB, ELISA
Application Notes
ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.
Target
Introduction
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The ''minimal RISC'' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by AGO2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. May inhibit translation initiation by binding to the 7-methylguanosine cap, thereby preventing the recruitment of the translation initiation factor eIF4-E. May also inhibit translation initiation via interaction with EIF6, which itself binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur. In some cases RISC-mediated translational repression is also observed for miRNAs that perfectly match the 3'' untranslated region (3''-UTR). Can also up-regulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3''-UTR of the TNF (TNF-alpha) mRNA and up-regulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.
Product Overview
This product is a mouse antibody against AGO2. It can be used for AGO2 detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
The length of the protein is 992 amino acids long. The sequence is show below: MILNARYLYIPCRQKQQQQQQQPQQQQQHQQKQQSQQQQQQQQQQQRSKEQGSQQQQRPQQQAQQQQPSQQQQQSQKQQHPQQQQQQRPQKQQQQFQQDQRPQQQQQQLQKQQQQQGQSWRPQSHDPSPASGSHSHSSSPSHAAALERVEEDFSKIKIDKQKIHSSALLPVLMRPNAHGTRGRAIKVEVNYIQLLLERLIPTAYHYDVDIQPAASRKWQRLAFSEFTKQMFPNHGFAFDGHKNAYAARRLQADVYEQEVKVRDEGRERRFKVAMKEAAVLDMTCLKTYMNNGSTLDKPMSAIQCLDIVLRTAYENNPRFIKFKKSIYVKPDRPDDIGSNHELWYGLFQSALLGARPFLNIDVSHKAFPTGGPVLRILVDMNRGQVPDRVTDWMSRDLHDFLKGMELSYTGPDGVSKLFKYNSIKSPANQQKFKLENGTEMTIDQYFRSKNKQLRYPSLPVLHVGSLVRNVMLPIELCSIPPGQALNKKHPDQCTQFIIRKSATDTATRKRKIMDLFNQIGYNNAPTIKEFGVSVGNNFETVDGRILDPPELSYRNDRRVKPMRGVWRADNMNFIIPSTEITRRELSWTILNLDGRTRPDAIDEFGRNIYQMSLKQGVQLQQFSMKNNFYEPRDMRFAVKDLDNIFDELKKRKIDLVFVVIPSPGRDGDVYAKVKQKAELCVGLLTQCIKSFTLDKKRGDMSTISNIWLKINAKTNGSNHVLAKNFKPPIARKTVMYVGADVTHPSPEQTNIPSVVGVAASYDLEGFRYNCCYRLQGPKDEMIRDLQNIVIKQLRQFKQTNQSLPELIMYYRDGVSEGQFQEVLTIELRAMQAAAASVQQGYKPNITFIVVQKRHHARFFPTANCPTEGRNNNVQPGTIVDRYITAPNQYQFFLVSHAAVQGVAKPTKYCVLYDDENCNPDQLQALTYYLCHMFTRCNRAVSYPAPTYYAHLAAYRGRVYIKDRPLNMNNLTKEYERMQIRTEIQDGHPMFFV.
