Mouse Anti-AKT1 Antibody (CBMOAB-00463HCB)


Cat: CBMOAB-00463HCB
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-00463HCB Monoclonal C. elegans (Caenorhabditis elegans), A. thaliana (Arabidopsis thaliana), Arabidopsis, Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Fruit fly (Drosophila melanogaster), Goat (Capra hircus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Zebrafish (Danio rerio), Marmoset, Pig (Sus scrofa), Rice (Oryza) WB, ELISA MO00463HB 100 µg
CBMOAB-00799FYA Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO00799FYA 100 µg
CBMOAB-18558FYB Monoclonal Rice (Oryza) WB, ELISA MO18558FYB 100 µg
CBMOAB-2000FYC Monoclonal A. thaliana (Arabidopsis thaliana) WB, ELISA MO2000FC 100 µg
CBMOAB-65413FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO65413FYA 100 µg
MO-AB-00104Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO00104Y 100 µg
MO-AB-07202R Monoclonal Cattle (Bos taurus) WB, ELISA MO07202R 100 µg
MO-AB-20764W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO20764W 100 µg
MO-AB-23666R Monoclonal Pig (Sus scrofa) WB, ELISA MO23666R 100 µg
MO-AB-36680W Monoclonal Goat (Capra hircus) WB, ELISA MO36680W 100 µg
MO-AB-50674W Monoclonal Marmoset WB, ELISA MO50674W 100 µg
MO-NAB-00364W Monoclonal Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Chicken (Gallus gallus), Zebrafish (Danio rerio) WB, IHC, IHC-P NW0290 100 µg
MO-DKB-00540W Polyclonal Fruit fly (Drosophila melanogaster) WB 100 µg
MO-DKB-01702W Polyclonal A. thaliana (Arabidopsis thaliana) WB 100 µg
MOFAB-204W Polyclonal Arabidopsis WB 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans), A. thaliana (Arabidopsis thaliana), Arabidopsis, Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Fruit fly (Drosophila melanogaster), Goat (Capra hircus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Zebrafish (Danio rerio), Marmoset, Pig (Sus scrofa), Rice (Oryza)
CloneMO00463HB
SpecificityThis antibody binds to C. elegans AKT1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.
Product OverviewMouse Anti-C. elegans AKT1 Antibody is a mouse antibody against AKT1. It can be used for AKT1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesSerine / threonine-protein kinase akt-1; EC 2.7.11.1; Protein kinase B akt-1; PKB akt-1; akt-1
Gene ID179424
UniProt IDQ17941
Protein RefseqThe length of the protein is 541 amino acids long. The sequence is show below: MSMTSLSTKSRRQEDVVIEGWLHKKGEHIRNWRPRYFMIFNDGALLGFRAKPKEGQPFPEPLNDFMIKDAATMLFEKPRPNMFMVRCLQWTTVIERTFYAESAEVRQRWIHAIESISKKYKGTNANPQEELMETNQQPKIDEDSEFAGAAHAIMGQPSSGHGDNCSIDFRASMISIADTSEAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLALGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEARTLLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYFDNEFTSQPVQLTPPSRSGALATVDEQEEMQSNFTQFSFHNVMGSINRIHEASEDNEDYDMG.
For Research Use Only | Not For Clinical Use.
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