Mouse Anti-AKT1 Antibody (CBMOAB-00463HCB)
Cat: CBMOAB-00463HCB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
CBMOAB-00463HCB | Monoclonal | C. elegans (Caenorhabditis elegans), A. thaliana (Arabidopsis thaliana), Arabidopsis, Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Fruit fly (Drosophila melanogaster), Goat (Capra hircus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Zebrafish (Danio rerio), Marmoset, Pig (Sus scrofa), Rice (Oryza) | WB, ELISA | MO00463HB | 100 µg | ||
CBMOAB-00799FYA | Monoclonal | Fruit fly (Drosophila melanogaster) | WB, ELISA | MO00799FYA | 100 µg | ||
CBMOAB-18558FYB | Monoclonal | Rice (Oryza) | WB, ELISA | MO18558FYB | 100 µg | ||
CBMOAB-2000FYC | Monoclonal | A. thaliana (Arabidopsis thaliana) | WB, ELISA | MO2000FC | 100 µg | ||
CBMOAB-65413FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO65413FYA | 100 µg | ||
MO-AB-00104Y | Monoclonal | Chicken (Gallus gallus) | WB, ELISA | MO00104Y | 100 µg | ||
MO-AB-07202R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO07202R | 100 µg | ||
MO-AB-20764W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO20764W | 100 µg | ||
MO-AB-23666R | Monoclonal | Pig (Sus scrofa) | WB, ELISA | MO23666R | 100 µg | ||
MO-AB-36680W | Monoclonal | Goat (Capra hircus) | WB, ELISA | MO36680W | 100 µg | ||
MO-AB-50674W | Monoclonal | Marmoset | WB, ELISA | MO50674W | 100 µg | ||
MO-NAB-00364W | Monoclonal | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Chicken (Gallus gallus), Zebrafish (Danio rerio) | WB, IHC, IHC-P | NW0290 | 100 µg | ||
MO-DKB-00540W | Polyclonal | Fruit fly (Drosophila melanogaster) | WB | 100 µg | |||
MO-DKB-01702W | Polyclonal | A. thaliana (Arabidopsis thaliana) | WB | 100 µg | |||
MOFAB-204W | Polyclonal | Arabidopsis | WB | 100 µg |
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | C. elegans (Caenorhabditis elegans), A. thaliana (Arabidopsis thaliana), Arabidopsis, Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Fruit fly (Drosophila melanogaster), Goat (Capra hircus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Zebrafish (Danio rerio), Marmoset, Pig (Sus scrofa), Rice (Oryza) |
Clone | MO00463HB |
Specificity | This antibody binds to C. elegans AKT1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Plasma Membrane; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. |
Product Overview | Mouse Anti-C. elegans AKT1 Antibody is a mouse antibody against AKT1. It can be used for AKT1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Serine / threonine-protein kinase akt-1; EC 2.7.11.1; Protein kinase B akt-1; PKB akt-1; akt-1 |
Gene ID | 179424 |
UniProt ID | Q17941 |
Protein Refseq | The length of the protein is 541 amino acids long. The sequence is show below: MSMTSLSTKSRRQEDVVIEGWLHKKGEHIRNWRPRYFMIFNDGALLGFRAKPKEGQPFPEPLNDFMIKDAATMLFEKPRPNMFMVRCLQWTTVIERTFYAESAEVRQRWIHAIESISKKYKGTNANPQEELMETNQQPKIDEDSEFAGAAHAIMGQPSSGHGDNCSIDFRASMISIADTSEAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLALGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEARTLLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYFDNEFTSQPVQLTPPSRSGALATVDEQEEMQSNFTQFSFHNVMGSINRIHEASEDNEDYDMG. |
For Research Use Only | Not For Clinical Use.
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