Rabbit Anti-APH1B Antibody (Cat MO-DKB-03572W)


Cat: MO-DKB-03572W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityC. elegans (Caenorhabditis elegans), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
SpecificityIt does not cross-react with other components of the gamma secretase complex or other proteins.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAffinity purified
Cellular LocalizationMembrane, Multi-Pass Protein

Application Information

ApplicationELISA, WB
Application NotesDot Blot: 1:10000
Enzyme-Linked Immunosorbent Assay: 1:10000
Western Blot: 1:500
The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]
Product OverviewThis product is a Rabbit antibody against the Aph 1b. It can be used for Aph 1b detection in Enzyme-Linked Immunosorbent Assay, Western Blot.
Alternative NamesAnterior pharynx defective 1B like; Gamma secretase subunit APH 1B; Presenilin stabilisation factor like; PRO1328; PSFL; TAAV 688
UniProt IDQ8WW43
For Research Use Only | Not For Clinical Use.
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